Tertiary 3-Aminopropenones and 3-Aminopropenoates: Their Preparation, with and without Lewis Acids, from Secondary Amines and 1,3-Diketo Compounds

Ramandeep Kaur Vohra; Jean-Luc Renaud; Christian Bruneau

doi:10.1055/s-2007-965916

PAPER

Tertiary 3-Aminopropenones and 3-Aminopropenoates: Their Preparation, with and without Lewis Acids, from Secondary Amines and 1,3-Diketo Compounds

Ramandeep Kaur Vohra, Jean-Luc Renaud, Christian Bruneau*
Catalyse et Organométalliques, UMR 6226: Sciences Chimiques de Rennes, CNRS-Université de Rennes 1, Campus de Beaulieu, 35042 Rennes Cedex, France
Fax: +33(2)23236939; e-Mail: christian.bruneau@univ-rennes1.fr;

Abstract

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Abstract

A direct method for the preparation of tertiary 3-aminopropenones and 3-aminopropenoates from β-diketones and β-keto esters, and secondary amines has been developed. The reaction is performed without solvent in the presence or absence of Lewis acid as catalyst, depending on the reactivity of both the amine and the diketo substrate.

Key words

catalysis - Lewis acid - enaminones - enamino esters - nucleophilic addition

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Referenzen

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