Syntheses of 2-Pyrones via Electrophilic Substitutions at C7 of 4-Hydroxy-6-methyl-2-pyrone through Mono- or Dianion Formation

Abstract

Electrophilic substitution protocols useful for functionalizations at C7 of 4-hydroxy-6-methyl-2-pyrone, or triacetic acid, are described here. This method was applied to the synthesis of annularin E.

Key words

dianion - 2-pyrones - 4-hydroxy-6-methyl-2-pyrone - triacetic acid - electrophilic substitution

References

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