Endoscopic ultrasonography

EUS in numbers

A computer search of the PubMed database (see appendix for search strategy) revealed a total of 255 papers devoted to endoscopic ultrasonography (EUS) that were published in English between August 2006 and mid-August 2007. These included 121 original papers (47 %), 78 case reports, comments, or letters (31 %), and 56 reviews or editorials (22 %). Both the numbers and breakdown of original papers by topic area and publishing journal ([Fig. 1]) are almost identical to those reported in a similar review 2 years ago [1]. It seems as though the research on EUS has reached a plateau.

Fig. 1 A total of 121 original papers on endoscopic ultrasonography (EUS) published in English between 1 August 2006 and 10 August 2007, broken down by: a research topic (by indication for EUS), b research topic (by EUS type: imaging only, EUS-guided biopsy, therapeutic EUS), c publishing journal.

References

• 1 Polkowski M. Endoscopic ultrasonography.  Endoscopy. 2006;  38 16-21
• 2 Khalid A, Nodit L, Zahid M. et al . Endoscopic ultrasound fine needle aspirate DNA analysis to differentiate malignant and benign pancreatic masses.  Am J Gastroenterol. 2006;  101 2493-2500
• 3 Nodit L, McGrath K M, Zahid M. et al . Endoscopic ultrasound-guided fine needle aspirate microsatellite loss analysis and pancreatic endocrine tumor outcome.  Clin Gastroenterol Hepatol. 2006;  4 1474-1478
• 4 Salek C, Benesova L, Zavoral M. et al . Evaluation of clinical relevance of examining K-ras, p16 and p53 mutations along with allelic losses at 9p and 18q in EUS-guided fine needle aspiration samples of patients with chronic pancreatitis and pancreatic cancer.  World J Gastroenterol. 2007;  13 3714-3720
• 5 Gomes A L, Bardales R H, Milanezi F. et al . Molecular analysis of c-Kit and PDGFRA in GISTs diagnosed by EUS.  Am J Clin Pathol. 2007;  127 89-96
• 6 Khalid A, Pal R, Sasatomi E. et al . Use of microsatellite marker loss of heterozygosity in accurate diagnosis of pancreaticobiliary malignancy from brush cytology samples.  Gut. 2004;  53 1860-1865
• 7 Khalid A, McGrath K M, Zahid M. et al . The role of pancreatic cyst fluid molecular analysis in predicting cyst pathology.  Clin Gastroenterol Hepatol. 2005;  3 967-973
• 8 Aithal G P, Anagnostopoulos G K, Tam W. et al . EUS-guided tissue sampling: comparison of ”dual sampling“ (Trucut biopsy plus FNA) with ”sequential sampling“ (Trucut biopsy and then FNA as required).  Endoscopy. 2007;  39 725-730
• 9 Storch I, Jorda M, Thurer R. et al . Advantage of EUS Trucut biopsy combined with fine-needle aspiration without immediate on-site cytopathologic examination.  Gastrointest Endosc. 2006;  64 505-511
• 10 Varadarajulu S, Fraig M, Schmulewitz N. et al . Comparison of EUS-guided 19-gauge Trucut needle biopsy with EUS-guided fine-needle aspiration.  Endoscopy. 2004;  36 397-401
• 11 Polkowski M, Gerke W, Nasierowska-Guttmejer A. et al . Endosonography-guided trucut biopsy of hypoechoic submucosal tumors of the stomach [abstract].  Endoscopy. 2006;  38 (Suppl II) A35
• 12 Verma D, Kapadia A, Eisen G M. et al . EUS vs MRCP for detection of choledocholithiasis.  Gastrointest Endosc. 2006;  64 248-254
• 13 Garrow D, Miller S, Sinha D. et al . Endoscopic ultrasound: a meta-analysis of test performance in suspected biliary obstruction.  Clin Gastroenterol Hepatol. 2007;  5 616-623
• 14 Romagnuolo J, Bardou M, Rahme E. et al . Magnetic resonance cholangiopancreatography: a meta-analysis of test performance in suspected biliary disease.  Ann Intern Med. 2003;  139 547-557
• 15 Pungpapong S, Wallace M B, Woodward T A. et al . Accuracy of endoscopic ultrasonography and magnetic resonance cholangiopancreatography for the diagnosis of chronic pancreatitis: a prospective comparison study.  J Clin Gastroenterol. 2007;  41 88-93
• 16 Lam E C, Rego R R, Paquin S C. et al . In patients referred for investigation because computed tomography suggests thickened gastric folds, endoscopic ultrasound is superfluous if gastroscopy is normal.  Am J Gastroenterol. 2007;  102 1200-1203