Dtsch Med Wochenschr 2007; 132(28/29): 1515-1524
DOI: 10.1055/s-2007-982063
CME-Beitrag | Review article
Kardiologie, Notfallmedizin
© Georg Thieme Verlag KG Stuttgart · New York

Notfall- und intensivmedizinische Versorgung von Patienten mit akutem Koronarsyndrom

Emergency therapy and intensive care of patients with acute coronary syndromesM. Weber1 , C. Hamm1
  • 1Kerckhoff-Klinik, Bad Nauheim
Further Information

Publication History

eingereicht: 23.3.2007

akzeptiert: 14.6.2007

Publication Date:
03 July 2007 (online)

Literatur

  • 1 Andersen H R, Nielsen T T, Rasmussen K. et al . A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction.  N Engl J Med. 2003;  349 733-742
  • 2 Antman E M, Anbe D T, Armstrong P W. et al . ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction - executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to revise the 1999 guidelines for the management of patients with acute myocardial infarction).  J Am Coll Cardiol. 2004;  44 671-719
  • 3 Antman E M, Cohen M, Radley D, McCabe C, Rush J, Premmereur J. et al . Assessment of the treatment effect of enoxaparin for unstable angina/non-Q-wave myocardial infarction. TIMI 11B-ESSENCE meta-analysis.  Circulation. 1999;  100 1602-1608
  • 4 Assessment of the Safety and Efficacy of a New Treatment Strategy with Percutaneous Coronary Intervention (ASSENT-4 PCI) investigators . Primary versus tenecteplase-facilitated percutaneous coronary intervention in patients with ST-segment elevation acute myocardial infarction (ASSENT-4 PCI): randomised trial.  Lancet. 2006;  367 569-578
  • 5 Babaev A, Frederick P D, Pasta D J, Every N, Sichrovsky T, Hochman J S. Trends in management and outcomes of patients with acute myocardial infarction complicated by cardiogenic shock.  JAMA. 2005;  294 448-454
  • 6 Bassand J P, Hamm C, Ardissino D. et al . Guidelines for the diagnosis and treatment of Non ST segment elevation acute coronary syndromes.  Eur Heart J. 2007;  in press
  • 7 Boersma E, Harrington R A, Moliterno D J. et al . Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials.  Lancet. 2002;  359 189-198
  • 8 Boersma E, Maas A C, Deckers J W, Simoons M L. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour.  Lancet. 1996;  348 771-775
  • 9 Cannon C P, Weintraub W S, Demopoulos L A. et al . Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban.  N Engl J Med. 2001;  344 1879-1887
  • 10 CAPRIE Steering Committee . A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE).  Lancet. 1996;  348 1329-1339
  • 11 Chen Z M, Pan H C, Chen Y P. et al . Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial.  Lancet. 2005;  366 1622-1632
  • 12 de Winter R J, Windhausen F, Cornel J H, Dunselman P H, Janus C L, Bendermacher P E. et al . Early invasive versus selectively invasive management for acute coronary syndromes.  N Engl J Med. 2005;  353 1095-1104
  • 13 Elsasser A, Mollmann H, Nef H. et al . Transcatheter closure of a ruptured ventricular septum after myocardial infarction using a venous approach.  Z Kardiol. 2005;  94 684-689
  • 14 Ferguson J J, Califf R M, Antman E M. et al . Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy: primary results of the SYNERGY randomized trial.  JAMA. 2004;  292 45-54
  • 15 Fibrinolytic Therapy Trialists’ (FTT) Collaborative Group . Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients.  Lancet. 1994;  343 311-322
  • 16 FRagmin and Fast Revascularisation during InStability in Coronary artery disease Investigators . Invasive compared with non-invasive treatment in unstable coronary-artery disease: FRISC II prospective randomised multicentre study.  Lancet. 1999;  354 708-715
  • 17 Freemantle N, Cleland J, Young P, Mason J, Harrison J. beta Blockade after myocardial infarction: systematic review and meta regression analysis.  BMJ. 1999;  318 1730-1737
  • 18 Hahn S A, Chandler C. Diagnosis and management of ST elevation myocardial infarction: a review of the recent literature and practice guidelines.  Mt Sinai J Med. 2006;  73 469-481
  • 19 Hamm C W. Guidelines: acute coronary syndrome (ACS). 1: ACS without persistent ST segment elevations.  Z Kardiol. 2004;  93 72-90
  • 20 Hamm C W. Guidelines: Acute coronary syndrome (ACS). II: Acute coronary syndrome with ST-elevation.  Z Kardiol. 2004;  93 324-341
  • 21 Hochman J S, Sleeper L A, Webb J G. et al . Early revascularization and long-term survival in cardiogenic shock complicating acute myocardial infarction.  JAMA. 2006;  295 2511-2515
  • 22 Hochman J S, Sleeper L A, Webb J G, Sanborn T A, White H D, Talley J D. et al . Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK Investigators. Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock.  N Engl J Med. 1999;  341 625-634
  • 23 Holmes D R, Berger P B, Hochman J S. et al . Cardiogenic shock in patients with acute ischemic syndromes with and without ST-segment elevation.  Circulation. 1999;  100 2067-2073
  • 24 Jeger R V, Tseng C H, Hochman J S, Bates E R. Interhospital transfer for early revascularization in patients with ST-elevation myocardial infarction complicated by cardiogenic shock - a report from the SHould we revascularize Occluded Coronaries for cardiogenic shocK? (SHOCK) trial and registry.  Am Heart J. 2006;  152 686-692
  • 25 Keeley E C, Boura J A, Grines C L. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials.  Lancet. 2003;  361 13-20
  • 26 Libby P, Theroux P. Pathophysiology of coronary artery disease.  Circulation. 2005;  111 3481-3488
  • 27 Neumann F J, Kastrati A, Pogatsa-Murray G. et al . Evaluation of prolonged antithrombotic pretreatment („cooling-off” strategy) before intervention in patients with unstable coronary syndromes: a randomized controlled trial.  Jama. 2003;  290 1593-1599
  • 28 Oler A, Whooley M A, Oler J, Grady D. Adding heparin to aspirin reduces the incidence of myocardial infarction and death in patients with unstable angina. A meta-analysis.  JAMA. 1996;  276 811-815
  • 29 Rajagopal V, Lincoff A M, Cohen D J. et al . Outcomes of patients with acute coronary syndromes who are treated with bivalirudin during percutaneous coronary intervention: an analysis from the Randomized Evaluation in PCI Linking Angiomax to Reduced Clinical Events (REPLACE-2) trial.  Am Heart J. 2006;  152 149-154
  • 30 Sanborn T A, Sleeper L A, Bates E R. et al . Impact of thrombolysis, intra-aortic balloon pump counterpulsation, and their combination in cardiogenic shock complicating acute myocardial infarction: a report from the SHOCK Trial Registry. SHould we emergently revascularize Occluded Coronaries for cardiogenic shocK?.  J Am Coll Cardiol. 2000;  (Suppl 3A) 36 1123-1129
  • 31 Silber S, Albertsson P, Aviles F F. et al. Guidelines for percutaneous coronary interventions . The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology.  Eur Heart J. 2005;  26 804-847
  • 32 Simoons M L. Effect of glycoprotein IIb/IIIa receptor blocker abciximab on outcome in patients with acute coronary syndromes without early coronary revascularisation: the GUSTO IV-ACS randomised trial.  Lancet. 2001;  357 1915-1924
  • 33 Steinhubl S R, Berger P B, Mann J T. et al . Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial.  JAMA. 2002;  288 2411-2420
  • 34 Stone G W, McLaurin B T, Cox D A. et al . Bivalirudin for patients with acute coronary syndromes.  N Engl J Med. 2006;  355 2203-2216
  • 35 The MIAMI Trial Research Group . Metoprolol in acute myocardial infarction (MIAMI). A randomised placebo-controlled international trial.  Eur Heart J. 1985;  6 199-226
  • 36 Van de Werf F, Ardissino D, Betriu A. et al . Management of acute myocardial infarction in patients presenting with ST-segment elevation. The Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology.  Eur Heart J. 2003;  24 28-66
  • 37 Yusuf S, Mehta S R, Chrolavicius S. et al . Effects of fondaparinux on mortality and reinfarction in patients with acute ST-segment elevation myocardial infarction: the OASIS-6 randomized trial.  JAMA. 2006;  295 1519-1530
  • 38 Yusuf S, Wittes J, Friedman L. Overview of results of randomized clinical trials in heart disease. I. Treatments following myocardial infarction.  JAMA. 1988;  260 2088-2093
  • 39 Yusuf S, Zhao F, Mehta S R, Chrolavicius S, Tognoni G, Fox K K. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation.  N Engl J Med. 2001;  345 494-502

Dr. med. Michael Weber

Kerckhoff Klinik, Abteilung für Kardiologie

Benekestraße 2-8

61231 Bad Nauheim

Phone: +49/6032/9960

Fax: +49/6032/9962313

Email: M.Weber@Kerckhoff-Klinik.de