DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2007; 132(46): 2455-2457DOI: 10.1055/s-2007-991673 Aktuelle Diagnostik & Therapie | Review article Hypertensiologie © Georg Thieme Verlag KG Stuttgart · New York Strategien zur Verbesserung der Therapietreue bei antihypertensiver Therapie Strategies to improve adherence with antihypertensive treatmentR. Düsing1 1Medizinische Poliklinik, Universitätsklinikum Bonn Recommend Article Abstract Buy Article Schlüsselwörter Therapietreue - Compliance - arterielle Hypertonie Key words compliance - adherence - arterial hypertension Full Text References Literatur 1 Bloom B S. Continuation of initial antihypertensive medication after 1 year of therapy. Clin Ther. 1998; 20 671-681 2 Burke T A, Sturkenboom M C, Lu S L, Wentworth C E, Lin Y, Rhoads G G. Discontinuation of antihypertensive drugs among newly diagnosed hypertensive patients in UK general practice. J Hypertens. 2006; 24 1193-1200 3 Caro J J, Salas M, Speckman J L, Raggio G, Jackson J D. Persistence with treatment for hypertension in actual practice. Can Med Assoc J. 1999; 160 31-37 4 Conlin P R, Gerth W C, Fox J, Roehm J B, Boccuzzi S J. Four-year persistence patterns among patients initiating therapy with the angiotensin II receptor antagonist Losartan versus other antihypertensive drug classes. Clin Ther. 2001; 23 1999-2010 5 Dahlof B, Sever P S, Poulter N R. ASCOT Investigators . Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA). Lancet. 2005; 366 895-906 6 Düsing R. Medikamentöse Therapie mit verblisterten Arzneimitteln: Möglichkeiten und Chancen. MMW-Fortschritte der Medizin Originalien. Nr. I/2007; 149 9-20 7 Düsing R. Therapietreue bei medikamentöser Behandlung. Dtsch Med Wochenschr. 2006; 131 H28-30 8 http://www.aardexgroup.com/index.php. 18.10.07. 9 http://www.assist-pharma.de/index.php. 18.10.07. 10 Metry J M, Meyer U A. Drug Regimen Compliance: Issues in Clinical Trials and Patient Management. John Wiley & Sons Chichester 1999 11 SHEP Cooperative Research Group . Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). J Am Med Assoc. 1991; 265 3255-3264 12 The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group . Major outcomes in high-risk hypertensiven patients radndomized to angiotensin-converting-enzyme inhibitor or calcium channel blocker vs diuretic. J Am Med Assoc. 2002; 288 2981-2997 13 Urquhart J, Vrijens B. Introduction to pharmionics: the vagaries in ambulatory patients’ adherence to prescribed drug dosing regimens and some of their clinical and economic consequences. In: Mann RD, Andrews EB Pharmacovigilance, 2nd ed. John Wiley & Sons Chichester 2007 14 Urquhart J, Vrijens B. Patient adherence to prescribed drug dosing regimens in ambulatory pharmacotherapy. In: Strom BL, Kimmel SE Textbook of Pharmacoepidemiology. John Wiley & Sons Chichester 2006 15 Urquhart J. Patient compliance with prescribed drug regimens: overview of the past 30 years of research. In: Nimmo WS, Tucker GT Clinical Measurement in Drug Evaluation. John Wiley & Sons Chichester 1995: 213-227 16 Urquhart J. The electronic medication event monitor - lessons for pharmacotherapy. Clin Pharmacokinet. 1997; 32 345-356 Prof. Dr. med. Rainer Düsing Universitätsklinikum Bonn, Medizinische Poliklinik Wilhelmstr. 35-37 53111 Bonn Phone: 0228/287-22343 Fax: 0228/287-22593 Email: duesing@uni-bonn.de