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Am J Perinatol 1995; 12(2): 132-134
DOI: 10.1055/s-2007-994424
ORIGINAL ARTICLE

© 1995 by Thieme Medical Publishers, Inc.

Intrauterine Diagnosis and Management of Transient Myeloproliferative Disorder

Nicola Strobelt, Alessandro Ghidini, Anna Locatelli, Patrizia Vergani, Silvana Mariani, Andrea Biondi
  • Departments of Obstetrics and Gynecology, and Pediatrics, Ospedale S. Gerardo, Monza, III Branch of the University of Milan, Milan, Italy; and from the Department of Obstetrics, Gynecology, and Reproductive Sciences, Mount Sinai School of Medicine, New York, New York
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Publication History

Publication Date:
04 March 2008 (online)

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ABSTRACT

Transient myeloproliferative disorders can be associated with hydrops in Down syndrome fetuses. No cases of prenatal management of such a condition have been reported in the literature. We report a case of myeloproliferative disorder diagnosed by cordocentesis at 31 weeks in a Down syndrome fetus with pericardial effusion. A pericardiocentesis was performed at the first signs of hydrops and successfully improved fetal cardiac function, allowing for continuation of pregnancy.

Keywords

Transient myeloproliferative disorders - Down syndrome - hydrops fetalis - leukemia

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