ABSTRACT
Posterior urethral valves (PUV) are a frequent cause of urinary tract obstruction
in infant males and may be diagnosed by antenatal ultrasound. PUV have been observed
in siblings and in identical twins. However, genetic factors in PUV are poorly understood.
In this article, we report the occurrence of PUV diagnosed antenatally in a fetus
whose father and paternal uncle were both treated for PUV in childhood. This is the
first reported case of PUV that we are aware of occurring in successive generations.
