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Am J Perinatol 1992; 9(1): 61-65
DOI: 10.1055/s-2007-994672
ORIGINAL ARTICLE

© 1992 by Thieme Medical Publishers, Inc.

Prenatal Transmission of Hepatitis B Virus to Neonates Born to Serum Hepatitis B Virus DNA-Positive Mothers

Chia C. Pao, Ding-Shyan Yao, Chieh-Yu Lin, T'sang-T'ang Hsieh
  • Department of Biochemistry, Chang Gung Medical College, and Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China
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Publication Date:
04 March 2008 (online)

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ABSTRACT

Hepatitis B virus (HBV) DNA was detected by in vitro enzymatic DNA amplification techniques in 66.7% (six of nine) of hepatitis B virus surface antigen (HBsAg)-positive and in 21.1% (7 of 33) of HBsAg-negative pregnant women. Fiveof the HBV DNA and HBsAg-positive women and one HBV DNA-positive but HBsAg-negative woman gave birth to infants positive for serum HBV DNA at time of birth. These results suggest that HBsAg-negative pregnant women are potentially capable of transmitting HBV DNA to their infants.