ABSTRACT
A case of primary cutaneous aspergillosis in a very low birthweight infant that responded
to medical therapy is reported. Knowledge of the potential pathogenic role of this
organism in neonatal skin lesions is important because of resistance to standard empirical
antibacterial therapy and the potential for dissemination and deep paren-chymal invasion.
Surgical excision may be necessary if cutaneous aspergillosis progresses despite systemic
antifungal therapy.
