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Planta Med 2008; 74(2): 178-181
DOI: 10.1055/s-2008-1034288
Natural Product Chemistry
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Phenylalkanoids and Monoterpene Analogues from the Roots of Rhodiola rosea

Zulfiqar Ali1 , Frank R. Fronczek2 , Ikhlas A. Khan1 , 3
  • 1National Center for Natural Products Research, School of Pharmacy, University of Mississippi, MS, USA
  • 2Department of Chemistry, Louisiana State University, Baton Rouge, LA, USA
  • 3Department of Pharmacognosy, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, MS, USA
Further Information

Publication History

Received: October 16, 2007 Revised: December 11, 2007

Accepted: December 14, 2007

Publication Date:
31 January 2008 (online)

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Abstract

Roots extract of Rhodiola rosea L. is the source of important commercial preparations widely used throughout Europe, Asia, and the USA. Phytochemical investigation of the roots of Rhodiola rosea afforded 17 compounds, belonging to the phenylalkanoids and monoterpene analogues. Their structures were determined by spectroscopic and chemical methods. Rhodioloside F (1) was found to be new. The X-ray crystallographic study on salidroside (7) and the complete NMR data of 5 (mongrhoside) and 1a [(-)-rosiridol] are also described.

Key words

Rhodiola rosea - Crassulaceae - Rhodioloside F - Salidroside - X-ray crystallography

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Ikhlas A. Khan

National Center for Natural Products Research

University of Mississippi

University

MS 38677

USA

Phone: +1-662-915-7821

Fax: +1-662-915-7989

Email: ikhan@olemiss.edu

    www.thieme-connect.de/ejournals/toc/plantamedica