Kutanes T-Zell-Lymphom vom Typ der Mycosis fungoides im Bereich des Lides und des Tränenweges

Hassane Aaliouet; Jens Martin Rohrbach; Thomas-Michael Wohlrab; Hans-Peter Horny; Karsten Sönnichsen

doi:10.1055/s-2008-1035016

Klinische Monatsblätter für Augenheilkunde, Inhaltsverzeichnis

Klin Monbl Augenheilkd 1997; 210(1): 62-64
DOI: 10.1055/s-2008-1035016

Diagnostisches Forum

Kutanes T-Zell-Lymphom vom Typ der Mycosis fungoides im Bereich des Lides und des Tränenweges

Cutaneous T-cell-lymphoma (CTCL) of the Mycosis Fungoides Type in the Lid and Lacrimal Sac AreaHassane Aaliouet¹ , Jens Martin Rohrbach¹ , Thomas-Michael Wohlrab¹ , Hans-Peter Horny² , Karsten Sönnichsen³

¹Universitäts-Augenklinik, Abteilung I (Allgemeine Augenheilkunde mit Poliklinik; Ärztlicher Direktor: Prof. Dr. H.-J. Thiel)
²Pathologisches Institut der Universität (Ärztlicher Direktor: Prof. Dr. B. Bültmann)
³Universitäts-Hautklinik (Ärztlicher Direktor: Prof. Dr. G. Rassner)

Abstract

Summary

Patient A 62-year-old former miner with silicosis of the lungs but otherwise in good general condition presented with a solid nodule in the nasal left lid area for a duration of three months Because of a central ulceration the reference diagnosis was basalioma. The tumour infiltrated the nasal part of the upper and lower eyelid and the tear ducts so that these were unrinseable. Similar lesions have been present since two years in other skin regions.

Methods Two cutaneous biopsies confirmed the diagnosis of a Mycosis fungoides without detectable expression of the CD30-antigen. Medical investigation finally revealed hepatosplenomegaly and cervical, inguinal and abdominal lymph node involvement. A lymph node biopsy three months after presentation again showed a T-cell-lymphoma which was CD30-positive now.

Therapy Systemic polychemotherapy was started. The lid lesions completely resolved, and the tear ducts were rinseable again.

Schlüsselwörter

Mycosis fungoides - kutanes T-Zell-Lymphom - CD30-Antigen - Lidtumor - Tränenwege

Key words

Mycosis fungoides - cutaneous T-cell-lymphoma - CD30-antigen - lid tumour - tear ducts

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