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DOI: 10.1055/s-2008-1038363
© Georg Thieme Verlag KG Stuttgart · New York
Immunohistochemical Findings in Rectal Duplication Mimicking Rectal Prolapse
Publikationsverlauf
received October 12, 2007
accepted after revision December 19, 2007
Publikationsdatum:
14. August 2008 (online)

Abstract
Alimentary tract duplications represent rare anomalies, with only 5 % occurring in the rectum. The variety in clinical presentation may lead to a delay in diagnosis or to incorrect and multiple surgical procedures. We report the clinical, histological and immunohistochemical characteristics of a rectal duplication occurring in a 3-month-old male with an unusual clinical presentation. Using routine histology and immunohistochemistry, the rectal duplication showed the diffuse presence of gastric mucosa with a characteristic immunophenotype (i.e., diffuse cytokeratin 7 positivity and scattered chromogranin immunoreactivity). As far as we know, this is the first report showing an immunohistochemical differentiation pattern of gastric lining in a rectal duplication. Our results, showing the presence of gastric mucosa, are suggestive of a possible origin from the embryonic foregut.
Key words
rectal duplication - immunohistochemistry - gastrointestinal malformation - neonatal surgery
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Dr. Roberta Macchieraldo
Department of Pediatric Surgery
Regina Margherita Children's Hospital
Piazza Polonia 94
10126 Turin
Italy
eMail: roberta.mac@tiscali.it