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Am J Perinatol 1994; 11(3): 192-193
DOI: 10.1055/s-2008-1040743
ORIGINAL ARTICLE

© 1994 by Thieme Medical Publishers, Inc.

Hemophilia B in a Neonate: Unusual Early Spontaneous Gastrointestinal Bleeding

Orit Reish, Elhanan Nachum, Nora Naor, Jacob Ghoshen, Paul Merlob
  • Departments of Neonatology and Pediatric Hematology/Oncology, Beilinson Medical Center, Petah Tiqva, Israel; and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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Publication Date:
04 March 2008 (online)

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ABSTRACT

A full-term male, healthy newborn infant suddenly developed melena and rectal fresh blood oozing at age of 4 days. He is the second patient described in the literature presenting a spontaneous gastrointestinal bleeding in the neonatal period as the first clinical manifestation of hemophilia B. The early appearance and severity of the hemorrhage, its short duration, and good response to Factor IX (inefficiency of vitamin K) was the characteristics of the affected neonate. Whenever a newborn presents early spontaneous gastrointestinal bleeding, hemophilia B should be considered a possible etiology and blood coagulation studies should be performed accordingly.