Untersuchung der Schleimhautverträglichkeit von Endorfer Jod-Thermalsole an der Konjunktiva von Kaninchen

Zusammenfassung

An der Konjunktiva von Kaninchen wurde die Endorfer Jod-Thermalsole im Vergleich zu einer physiologischen Kochsalzlösung hinsichtlich ihrer lokalen Reizwirkung untersucht, wobei sich eine gute Verträglichkeit zeigte. Die Anwendung am Auge scheint somit unbedenklich.

Summary

The conjunctivae of nine rabbits of the same breed were used to compare the local compatibility of the Endorfer Jod-Thermalsole with that of a physiological NaCl solution. The neuroleptanalgesics were administered using perfusion techniques. The reddening thus caused was used to measure the degree of inflammation. The reddening was assessed subjectively according to a points system and then photographed under the same conditions for greater objectivity. The slides are archived in the Institute for Balneology and Climatology of the University of Munich. After administering the Endorfer Jod-Thermalsole to the mucous membranes for 30 and 60 minutes there was no difference in compatibility as compares to a physiological NaCl solution. No appreciable irritation occurred.