Thrombosis and Haemostasis, Table of Contents Thromb Haemost 2004; 92(06): 1171DOI: 10.1160/TH04-10-0674 Editorial Focus Schattauer GmbH Antithrombin extends its job Johan W.M. Heemskerk 1 Department of Biochemistry, CARIM, University of Maastricht, The Netherlands › Author Affiliations Recommend Article Abstract Buy Article Full Text References References 1 Senden NHM, Jeunhomme TMA, Heemskerk JWM. et al. Factor Xa induces cytokine production and expression of adhesion molecules in human umbilical vein endothelial cells. J Immunol 1998; 161: 4318-24. 2 Camerer E. et al. Tissue factor- and factor Xdependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci USA 2000; 97: 5255-60. 3 Zaman GJR, Conway EM. The elusive factor Xa receptor: failure to detect transcripts that correspond to the published sequence of EPR1. Blood 2000; 96: 145-8. 4 Oelschläger C, Römisch J, Staubitz A. et al. Antithrombin III inhibits nuclear factor κB activation in human monocytes and vascular endothelial cells. Blood 2002; 99: 4015-20. 5 Uchiba M. et al. Inhibition of the endothelial cell activation by antithrombin in vitro . Thromb Haemost 2004; 92: 1420-7. 6 O’Reilly MS. et al. Antiangiogenic activity of the cleaved conformation of the serpin antithrombin. Science 1999; 285: 1926-8.