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Thromb Haemost 2006; 95(01): 1-2
DOI: 10.1160/TH05-12-0790
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Schattauer GmbH

Ways to bypass a blocked tenase complex

Edward G. D. Tuddenham
1   Faculty of Medicine, Imperial College, MRC Clinical Sciences Centre, London, United Kingdom
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Publication History

Received 07 December 2005

Accepted 07 December 2005

Publication Date:
28 November 2017 (online)

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  • References

  • 1 Addis T. The pathogenesis of hereditary haemophilia. Pathol Bacteriol 1911; 15: 427-52.
    CrossrefPubMedSearch in Google Scholar
  • 2 Osterud B, Rapaport SI. Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for the initiation of blood coagulation. Proc Natl Acad Sci USA 1977; 74: 5260-4.
    CrossrefPubMedSearch in Google Scholar
  • 3 Broze Jr GJ, Warren LA, Novotney WF. et al. The role of tissue factor pathway inhibitor in a revised coagulation cascade. Blood 1988; 71: 335-43.
    PubMedSearch in Google Scholar
  • 4 Wielders SJH, Beguin S, Hemker HC. et al. Factor XI-dependent reciprocal thrombin generation consolidates blood coagulation when tissue factor is not available. Arterioscler Thromb Vasc Biol 2004; 24: 1138-42.
    CrossrefPubMedSearch in Google Scholar
  • 5 Hedner U, Glazer S, Pingel K. et al. Successful use of recombinant factor VIIa in patient with severe haemophilia A during synovectomy. Lancet 1988; 2: 1193.
    PubMedSearch in Google Scholar
  • 6 Butenas S, Brummel KE, Branda RF. et al. Mechanism of factor VIIa-dependent coagulation in hemophilia blood. Blood 2002; 99: 923-30.
    CrossrefPubMedSearch in Google Scholar
  • 7 Monroe DM, Roberts HR. Mechanism of action of high-dose factor VIIa: points of agreement and disagreement. Arterioscler Thromb Vasc Biol 2003; 23: 8-9.
    CrossrefPubMedSearch in Google Scholar
  • 8 Hrachovinova I, Cambien B, Hafezi-Moghadam A. et al. Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A. Nat Med 2003; 9: 1020-5.
    CrossrefPubMedSearch in Google Scholar
  • 9 Nordfang O, Valentin S, Beck TC. et al. Inhibition of extrinsic pathway inhibitor shortens the coagulation time of normal plasma and of hemophilia plasma. Thromb Haemost 1991; 66: 464-7.
    Thieme ConnectPubMedSearch in Google Scholar
  • 10 Erhardtsen E, Ezban M, Madsen MT. et al. Blocking of tissue factor pathway inhibitor (TFPI) shortens the bleeding time in rabbits with antibody induced haemophilia A. Blood Coagul Fibrinolysis 1995; 6: 388-94.
    CrossrefPubMedSearch in Google Scholar
  • 11 Liu T, Scallan CD, Broze GJ. et al. Improved coagulation in bleeding disorders by non-anticoagulant sulphated poysaccharides (NASP). Thromb Haemost 2006; 95: 68-76.
    Thieme ConnectPubMedSearch in Google Scholar