DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 01 · Volume 95 · 2006 DOI: 10.1055/s-007-35497

Editorial Focus

1
Tuddenham, Edward G. D.: Ways to bypass a blocked tenase complex

Theme Issue Editorial Focus

3
Hirsch, Emilio: Signal transduction in inflammation

Theme Issue Article

5
Laudanna, Carlo; Alon, Ronen: Right on the spot
12
Bagorda, Anna; Mihaylov, Vassil A.; Parent, Carole A.: Chemotaxis: moving forward and holding on to the past
22
Del Prete, Annalisa; Locati, Massimo; Otero, Karel; Riboldi, Elena; Mantovani, Alberto; Vecchi, Annunciata; Sozzani, Silvano: Migration of dendritic cells across blood and lymphatic endothelial barriers
29
Hirsch, Emilio; Lembo, Giuseppe; Montrucchio, Giuseppe; Rommel, Christian; Costa, Carlotta; Barberis, Laura: Signaling through PI3Kγ: a common platform for leukocyte, platelet and cardiovascular stress sensing
36
Bazzoni, Gianfranco: Endothelial tight junctions: permeable barriers of the vessel wall
43
Inoue, Teruo; Kato, Toru; Hikichi, Yutaka; Hashimoto, Shigemasa; Hirase, Tetsuaki; Morooka, Toshifumi; Imoto, Yoshitaka; Takeda, Yuji; Sendo, Fujiro; Node, Koichi: Stent-induced neutrophil activation is associated with an oxidative burst in the inflammatory process, leading to neointimal thickening

Review Article

49
Blann, Andrew D.: Plasma von Willebrand factor, thrombosis, and the endothelium: The first 30 years
56
Righini, Marc; Paris, Samuel; Le Gal, Grégoire; Laroche, Jean-Pierre; Perrier, Arnaud; Bounameaux, Henri: Clinical relevance of distal deep vein thrombosis

Rapid and Short Communication

65
Gulesserian, Talin; Hron, Gregor; Endler, Georg; Eichinger, Sabine; Wagner, Oswald; Kyrle, Paul A.: Marburg I polymorphism of factor VII-activating protease and risk of recurrent venous thromboembolism

Blood Coagulation, Fibrinolysis and Cellular Haemostasis

68
Liu, Tongyao; Scallan, Ciaran D.; Broze, George J.; Patarroyo-White, Susanna; Pierce, Glenn F.; Johnson, Kirk W.: Improved coagulation in bleeding disorders by Non-Anticoagulant Sulfated Polysaccharides (NASP)
77
Schroeder, Verena; Meili, Esther; Cung, Trinh; Schmutz, Peter; Kohler, Hans P.: Characterisation of six novel A-subunit mutations leading to congenital factor XIII deficiency and molecular analysis of the first diagnosed patient with this rare bleeding disorder

Platelets and Blood Cells

85
Nigatu, Ayele; Sime, Wondossen; Gorfu, Gezahegn; Geberhiwot, Tarekegn; Andurén, Ingegerd; Ingerpuu, Sulev; Doi, Masayuki; Tryggvason, Karl; Hjemdahl, Paul; Patarroyo, Manuel: Megakaryocytic cells synthesize and platelets secrete α5-laminins, and the endothelial laminin isoform laminin 10 (α5β1γ1) strongly promotes adhesion but not activation of platelets
94
Pereira, Jaime; Alfaro, Gino; Goycoolea, Manuela; Quiroga, Teresa; Ocqueteau, Mauricio; Massardo, Loreto; Pérez, Carol; Sáez, Claudia; Panes, Olga; Matus, Valeria; Mezzano, Diego: Circulating platelet-derived microparticles in systemic lupus erythematosus
100
Hartley, Paul S.; Savill, John; Brown, Simon B.: The death of human platelets during incubation in citrated plasma involves shedding of CD42b and aggregation of dead platelets

Endothelium and Vascular Development

107
Demyanets, Svitlana; Pfaffenberger, Stefan; Kaun, Christoph; Rega, Gersina; Speidl, Walter S.; Kastl, Stefan P.; Weiss, Thomas W.; Hohensinner, Philipp J.; Dietrich, Wolf; Tschugguel, Walter; Bochkov, Valery N.; Awad, Ezzat M.; Maurer, Gerald; Huber, Kurt; Wojta, Johann: The estrogen metabolite 17β-dihydroequilenin counteracts interleukin-1α induced expression of inflammatory mediators in human endothelial cells in vitro via NF-κB pathway
117
Maccarrone, Mauro; Fiori, Anna; Bari, Monica; Granata, Filippo; Gasperi, Valeria; De Stefano, M. Egle; Finazzi-Agrò, Alessandro; Strom, Roberto: Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial cells

Cardiovascular Biology and Cell Signalling

128
Li, Yi-Heng; Liu, Shu-Lin; Shi, Guey-Yueh; Tseng, Guan-Hsiung; Liu, Ping-Yen; Wu, Hua-Lin: Thrombomodulin plays an important role in arterial remodeling and neointima formation in mouse carotid ligation model
134
Thorand, Barbara; Baumert, Jens; Döring, Angela; Schneider, Andrea; Chambless, Lloyd; Löwel, Hannelore; Kolb, Hubert; Koenig, Wolfgang: Association of cardiovascular risk factors with markers of endothelial dysfunction in middle-aged men and women

Cellular Proteolysis and Oncology

142
Ho-Tin-Noé, Benoît; Meilhac, Olivier; Rossignol, Patrick; Lijnen, H. Roger; Anglés-Cano, Eduardo: Dual effect of apolipoprotein(a) on plasmin(ogen)-induced apoptosis through modulation of cell detachment of adherent cells
151
Schmidt, Roland; Redecke, Vanessa; Breitfeld, Yoshi; Wantia, Nina; Miethke, Thomas; Massberg, Steffen; Fischel, Sina; Neumann, Franz-Josef; Schömig, Albert; May, Andreas E.: EMMPRIN (CD 147) is a central activator of extracellular matrix degradation by Chlamydia pneumoniae-infected monocytes.

Animal Models

159
Sudo, Toshiki; Ito, Hideki; Kimura, Yukio: Genetic strain differences in platelet aggregation of laboratory mice
166
Zhang, Li; Zhang, Zheng Gang; Liu, Xianshuang; Hozeska, Ann; Stagliano, Nancy; Riordan, William; Lu, Mei; Chopp, Michael: Treatment of embolic stroke in rats with bortezomib and recombinant human tissue plasminogen activator
174
Semeraro, Fabrizio; Voros, Gabor; Collen, Désiré; Lijnen, H. Roger: Impairment of adipose tissue development by hypoxia is not mediated by plasminogen activator inhibitor-1

New Technologies, Diagnostic Tools and Drugs

182
Dorweiler, Bernhard; Torzewski, Michael; Dahm, Manfred; Ochsenhirt, Viola; Lehr, Hans-Anton; Lackner, Karl J.; Vahl, Christian-Friedrich: A novel in vitro model for the study of plaque development in atherosclerosis

Case Report

190
Rieger, Christina; Rank, Andreas; Fiegl, Michael; Tischer, Johanna; Schiel, Xaver; Ostermann, Helmut; Kolb, Hans-Jochem: Allogeneic stem cell transplantation as a new treatment option for patients with severe Bernard-Soulier Syndrome
192
Herman, Darja; Peternel, Polona; Stegnar, Mojca; Breskvar, Katja; Dolzan, Vita: A novel sequence variant in exon 7 of CYP2C9 gene (CYP2C9*24) ina patient on warfarin therapy
195
Stanchev, Hristo; Philips, Malou; Villoutreix, Bruno O.; Aksglæde, Lise; Lethagen, Stefan; Thorsen, Sixtus: Prothrombin deficiency caused by compound heterozygosity for two novel mutations in the prothrombin gene associated with a bleeding tendency
199
Gueddi, Salah; Righini, Marc; Mezger, Nathalie; Morard, Isabelle; Kaiser, Laurent; Giostra, Emiliano; Bounameaux, Henri; Angelillo-Scherrer, Anne: Portal vein thrombosis following a primary cytomegalovirus infection in an immunocompetent adult

Letter to the Editor

202
Tayebjee, Muzahir H.; Lip, Gregory Y. H.; Tan, Kiat T.; MacFadyen, Robert J.: Abnormal circulating neutrophil linked matrix metalloproteinase –9 in stable coronary artery disease