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DOI: 10.1160/TH06-03-0152
Long-term stability of relationships between reference materials for thromboplastins
Publication History
Received
15 March 2006
Accepted after resubmission
07 June 2006
Publication Date:
28 November 2017 (online)
Summary
Reference materials for thromboplastins are available from the World Health Organization (WHO) and the European Commission (EC). The long-term stability of the reference materials is an essential requirement and must be monitored. The relationship between two reference materials for rabbit thromboplastin, i. e. ERM-AD149 (EC) and RBT/90 (WHO), has been monitored in the period 1996–2002. No significant trend with time was detected. In addition,the relationship between ERM-AD149 and the reference material for bovine thromboplastin (i. e. OBT/79) has been determined in 1994 and in 2005 in multicentre studies (n = 11 and n = 9, respectively). No significant changes were observed in the relationships between these reference materials when all results were included (5% significance level).
Footnote: ERM-AD148 and ERM-AD149 are distributed by IRMM. As one of the institutes of the European Commission’s Joint Research Centre, IRMM is a non-profit organisation.
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References
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