The changing faces of tissue factor biology

 

^* Professor emeritus.

• References

• 1 Stormorken H, Paul A. Owren & The Golden Era of Haemostasis. Gazette Book; 2005
• 2 Cohen S, Chargaff E. Studies on the chemistry of blood coagulation. IX. The thromboplastic protein from lungs. J Biol Chem 1940; 136: 243-256.
• 3 Chargaff E. Studies on the mechanism of the thromboplastic effect. J Biol Chem 1947; 253-262.
• 4 Hvatum M, Prydz H. Studies on tissue thromboplastin. I. Solubilization with sodium deoxycholate. Biochim Biophys Acta 1966; 130: 92-101.
• 5 Nemerson Y, Pitlick F. Purification and characterization of the protein component of tissue factor. Biochemistry 1970; 9: 5100-5105.
• 6 Bjørklid E, Storm E, Prydz H. The protein component of human brain thromboplastin. Biochem Biophys Res Com 1973; 55: 969-976.
• 7 Bjørklid E, Storm E. Purification and some properties of the protein component of tissue thromboplastin from human brain. Biochem J 1977; 165: 89-96.
• 8 Bjørklid E, Storm-Mathisen J, Storm E. et al. Localization of tissue thromboplastin in the human brain. Thromb Haemost 1977; 37: 91-97.
• 9 Fisher K, Gorman CM, Vehar GA. et al. Cloning and expression of human tissue factor cDNA. Thromb Res 1987; 48: 89-99.
• 10 Morrissey JH, Fakhrai H, Edgington TS. Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade. Cell 1987; 50: 129-135.
• 11 Scarpati EM, Wen D, Brozejr GJ. et al. Human tissue factor: cDNA sequence and chromosome localization of the gene. Biochemistry 1987; 26: 5234-5238.
• 12 Spicer EK, Horton R, Bloem L. et al. Isolation of cDNA clones coding for human tissue factor: Primary structure of the protein and cDNA. Biochemistry 1987; 84: 5148-5152.
• 13 Mackman N, Morrissey JH, Fowler B. et al. Complete sequence of the human tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade. Biochemistry 1989; 28: 1755-1762.
• 14 Carson SD. Tissue factor gene localized to human chromosome 1 (1pter - 1p21). Science 1985; 229: 991-993.
• 15 Brand K, Fowler B, Edgington TS. et al. Tissue factor mRNA in THP-1 monocytic cells is regulated at both transcriptional and posttranscriptional levels in response to lipopolysaccaride. Mol Cell Biol 1991; 11: 4732-4738.
• 16 van der Logt CPE, Reitsma PH, Bertina RM. Alternative splicing is responsible for the presence of two tissue factor mRNA species in LPS stimulated human monocytes. Thromb Haemost 1992; 67: 272-276.
• 17 Bach R, Konigsberg WH, Nemerson Y. Human Tissue Factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine. Biochemistry 1988; 27: 4227-4231.
• 18 Bazan JF. Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci 1990; 87: 6934-6938.
• 19 Harlos K, Martin DMA, O’Brien DP. et al. Crystal structure of the extracellular region of human tissue factor. Nature 1994; 370: 662-666.
• 20 Bogdanov V, Balasubramanian V, Hathcock J. et al. Alternatively spliced human tissue factor: circulating, soluble, thrombogenic protein. Nature Medicine 2003; 9: 458-462.
• 21 Chand H, Ness S, Kisiel W. Identification of a novel human tisue factor splice variant that is upregulated in tumor cells. Int J Cancer 2006; 118: 1713-1720.
• 22 Szotowski B, Antoniak S, Rauch R. Alternaltively spliced tissue factor: A previously unknown piece in the puzzle of hemostasis. Trends Cardiovasc Med 2006; 16: 177-182.
• 23 Censarek P, Bobbe A, Grandoch M, Schrör K, Weber A-A. Alternatively spliced human tissue factor (asHTF) is not procoagulant. Thromb Haemost 2007; 97: 11-14.
• 24 Prydz H, Lyberg T, Deteix P. et al. In vitro stimulation of tissue thromboplastin (factor III) activity in human monocytes by immune complexes and lectins. Thromb Res 1979; 15: 465-474.
• 25 Lyberg T, Galdal KS, Prydz H. Synthesis of thromboplastin protein in endothelial cells. Cambridge, UK: University Press; 1981
• 26 Camerer E, Kolstø A-B, Prydz H. Cell biology of tissue factor, the principal initiator of blood coagulation. Thromb Res 1996; 81: 1-41.
• 27 Pettersen KS, Wiiger MT, Narahara N. et al. Induction of tissue factor synthesis in human umbilical vein endothelial cells involves protein kinase C. Thromb Haemost 1992; 67: 473-477.
• 28 Ternisien C, Ramani M, Ollivier V. et al. Endotoxin-induced tissue factor in human monocytes is dependent upon protein kinase C activation. Thromb Haemost 1993; 70: 800-806.
• 29 Lang D, Terstesse M, Dohle F. et al. Protein kinase C (PKC) dependent induction of tissue factor (TF) by mesangial cells in response to inflammatory mediators and release during apoptosis. Br J Pharmacol 2002; 137: 1116-1124.
• 30 Andoh K, Pettersen KS, Filion-Myklebust C. et al. Observations on the cell biology of tissue factor in endothelial cells. Thromb Haemost 1990; 63: 298-302.
• 31 Wiiger MT, Pringle S, Pettersen KS. et al. Effects of binding of ligand (FVIIa) to induced tissue factor in human endothelial cells. Thromb Res 2000; 98: 311-321.
• 32 Hetland O, Brovold A, Holme R. et al. Thromboplastin (tissue factor) in plasma membranes of human monocytes. Biochem J 1985; 3: 735-743.
• 33 Drake TA, Ruf W, Morrissey JH. et al. Functional tissue factor is entirely cell surface expressed on lipo-polysaccaride-stimulated human blood monocytes and a constitutively tissue factor-producing neoplastic cell line. J Cell Biol 1989; 109: 389-395.
• 34 Schecter AD, Giesen PLA, Taby O. et al. Tissue factor expression in human arterial smooth muscle cells. TF is present in three cellular pools after growth factor stimulation. J Clin Invest 1997; 100: 2276-2285.
• 35 Narahara N, Enden T, Wiiger M. et al. Polar expression of tissue factor in human umbilical vein endothelial cells. Arterioscler ThrombVascBiol 1994; 14: 1815-1820.
• 36 Camerer E, Pringle S, Skartlien AH. et al. Opposite sorting of tissue factor in human umbilical vein endothelial cells and Madin-Darby canine kidney epithelial cells. Blood 1996; 88: 1339-1349.
• 37 Sevinsky JR, Rao LVM, Ruf W. Ligand induced protease receptor translocation into caveolae: A mechanism for regulating cell surface proteolysis of the tissue factor dependent coagulation pathway. J Cell Biol 1996; 133: 295-304.
• 38 Mulder AB, Smit JW, Bom VJJ. et al. Association of smooth muscle cell tissue factor with caveolae. Blood 1996; 88: 1306-1313.
• 39 Mandal S, Pendurthi UR, Rao LVM. Cellular localization and trafficking of tissue factor. Blood 2006; 107: 4746-4753.
• 40 Gladhaug Å, Prydz H. Purification of the coagulation factors VII and X from human serum. Some properties of factor VII. Biochim Biophys Acta 1970; 215: 105-111.
• 41 Gibbs CS, McCurdy SN, Leung LLK. et al. Identification of the Factor VIIa binding site on tissue factor by homologous loop swap and alanine scanning mutagenesis. Biochemistry 1994; 33: 14003-14010.
• 42 Ruf W, Schullek JR, Stone MJ. et al. Mutational mapping of functional residues in tissue factor: Identification of factor VII recognition determinants in both structural modules of the predicted cytokine receptor homology domain. Biochemistry 1994; 33: 1565-1572.
• 43 Kelley RF, Costas K, O’Connell M. et al. Analysis of Factor VIIa binding site on human tissue factor: Effects of tissue factor mutations on the kinetics and thermodynamics of binding. Biochemistry 1995; 34: 10383-10392.
• 44 McVey JH, Boswell E, Mumford AD. et al. Factor VII deficiency and the FVII mutation database. Human Mutation 2001; 17: 3-17.
• 45 Dickinson CD, Kelly CR, Ruf W. Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor VIIa. PNAS 1996; 93: 14379.
• 46 Banner DW, D’Arcy A, Chène C. et al. The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor. Nature 1996; 380: 41-46.
• 47 Ruf W, Dickinson CD. Allosteric regulation of the cofactor-dependent serine protease coagulation factor VIIa. trends in cardiovascular medicine 1998; 8: 350-356.
• 48 Eigenbrot C. Structure, function, and activation of coagulation factor VII. Current protein and peptide science 2002; 3: 287-299.
• 49 Lawson JH, Butenas S, Mann KG. The evaluation of complex-dependent alterations in human factor VIIa. J Biol Chem 1992; 267: 4834.
• 50 Røttingen J-A, Enden T, Camerer E. et al. Binding of human factor VIIa to tissue factor induces Ca²⁺ signals in J82 cells, transfected COS-1 cells, MDCK cells and in human endothelial cells induced to synthesise tissue factor. J Biol Chem 1995; 270: 4650-4660.
• 51 Boukamp P, Petrussevska R, Breitkreutz D. et al. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 1988; 106: 761-771.
• 52 Røttingen J-A, Camerer E, Mathiesen I. et al. Synchronized Ca²⁺oscillations induced in Madin Darby canine kidney cells by bradykinin and thrombin but not by ATP. Cell Calcium 1997; 21: 195-211.
• 53 Camerer E, Røttingen J-A, Gjernes E. et al. Coagulation factors VIIa and Xa induce cell signaling leading to up-regulation of the egr-1 gene. J Biol Chem 1999; 274: 32225-32233.
• 54 Poulsen LK, Jacobsen N, Sørensen BB. et al. Signal transduction via the mitogen-activated protein kinase pathway induced by binding of coagulation factor VIIa to tissue factor. J Biol Chem 1998; 273: 6228-6232.
• 55 Versteeg HH, Bresser HL, Spek CA. et al. Regulation of the p21Ras-MAP kinase pathway by factor VIIa. J Thromb Haemost 2003; 1: 1012-1018.
• 56 Versteeg HH, Hoedemaeker I, Diks SH. et al. Factor VIIa/Tissue Factor-induced signaling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac. J Biol Chem 2000; 275: 28750-28756.
• 57 Versteeg HH, Sorensen BB, Slofstra SH. et al. VIIa/ tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation. J Biol Chem 2002; 277: 27065-27072.
• 58 Pendurthi UR, Alok D, Rao LVM. Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: Up-regulation of Wiiger, Prydz: Changing faces of tissue factor biology poly (A) polymerase. Proc Natl Acad Sci 1997; 94: 12598-12603.
• 59 Pendurthi UR, Allen KE, Ezban M. et al. Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible down-stream mediators in factor VIIa^. Tissue Factor-induced signal transduction. J Biol Chem 2000; 275: 14632-14641.
• 60 Camerer E, Gjernes E, Wiiger M. et al. Binding of factor VIIa to tissue factor on keratinocytes induces gene expression. J Biol Chem 2000; 275: 6580-6585.
• 61 Wang X, Gjernes E, Prydz H. Factor VIIa induces tissue factor-dependent up-regulation of interleukin-8 in a human keratinocyte line. J Biol Chem 2002; 277: 23620-23626.
• 62 Sørensen BB, Freskgard PO, Nielsen LS. et al. Factor VIIa-induced p44/42 mitogen-activated protein kinase activation requires the proteolytic activity of factor VIIa and is independent of the tissue factor cytoplasmic domain. J Biol Chem 1999; 274: 21349-21354.
• 63 Coughlin SR. Protease-activated receptors in vascular biology. Thromb Haemost 2001; 86: 298-307.
• 64 Camerer E, Røttingen J-A, Iversen J-G. et al. Coagulation factors VII and X induce Ca²⁺ oscillations in Madin-Darby canine kidney cells only when proteolytically active. J Biol Chem 1996; 271: 29034-29042.
• 65 Camerer E, Huang W, Coughlin SR. Tissue factor and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci 2000; 97: 5255-5260.
• 66 Ahamed J, Ruf W. Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain. J Biol Chem 2004; 279: 23038-23044.
• 67 Dorfleutner A, Ruf W. Regulation of tissue factor cytoplasmic domain phosphorylation by palmitoylation. Blood 2003; 102: 3998-4005.
• 68 Wiiger MT, Prydz H. The epidermal growth factor receptor (EGFR) and proline rich tyrosine kinase 2 (PYK2) are involved in tissue factor dependent factor VIIa signalling in HaCaT cells. Thromb Haemost 2004; 92: 13-22.
• 69 Wiiger MT. Tissue factor and factor VII in coagulation and signal transduction. Faculty of Medicine, University of Oslo, 2004 (thesis).
• 70 Ahamed J, Versteeg HH, Kerver M. et al. Disulfide isomerization switches tissue factor from coagulation to cell signaling. Proc Natl Acad Sci 2006; 103: 13932-13937.
• 71 Fire A, Xu S, Montgomery MK. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811.
• 72 Elbashir S, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 2001; 15: 188-200.
• 73 Holen T, Amarzguioui M, Wiiger M. et al. Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucl Acids Res 2002; 30: 1757-1766.
• 74 Amarzguioui M, Peng Q, Wiiger MT. et al. Ex vivo and in vivo delivery of anti-tissue factor short interfering RNA inhibits mouse pulmonary metastasis of B16 melanoma cells. Clin Cancer Res 2006; 12: 4055-4061.