Including the life-time cumulative number of joint bleeds in the definition of primary prophylaxis

Thromb Haemost 2008; 99(05): 965
DOI: 10.1160/TH08-02-0097

Letters to the Editor

Schattauer GmbH

Authors

Ingrid E. M. den Uijl

¹Van Creveldkliniek/ Julius Center, UMC Utrecht, Utrecht, The Netherlands
Kathelijn Fischer

¹Van Creveldkliniek/ Julius Center, UMC Utrecht, Utrecht, The Netherlands

References
1 Schobess R, Kurnik K, Friedrichs F. et al. Effects of primary and secondary prophylaxis on the clinical expression of joint damage in children with severe haemophilia A. Results of a multicenter non-concurrent cohort study. Thromb Haemost 2008; 99: 71-76.
2 Kreuz W, Escuriola EC, Funk M. et al. Prevention of joint damage in hemophilic children with early prophylaxis. Orthopaede 1999; 28: 341-346.
3 Fischer K, van der Bom JG, Mauser-Bunschoten EP. et al. The effects of postponing prophylactic treatment on long-term outcome in patients with severe hemophilia. Blood 2002; 99: 2337-2341.
4 Pettersson H, Nilsson IM, Hedner U. et al. 1981. Radiologic evaluation of prophylaxis in severe haemophilia. Acta Paediatr Scand 1981; 70: 565-570.