Calcification inhibitors in vascular calciphylaxis associated with normal renal function

Vincent Brandenburg; Nadia Al-Fakhri; Katharina Nemeth; Claudia Goettsch; Leon J. Schurgers; Cees Vermeer; Lorenz C. Hofbauer; Michael Schoppet

doi:10.1160/TH12-07-0484

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 2012; 108(06): 1241-1243
DOI: 10.1160/TH12-07-0484

Letters to the Editor

Schattauer GmbH

Calcification inhibitors in vascular calciphylaxis associated with normal renal function

Vincent Brandenburg^*

¹Department of Cardiology, University Hospital Aachen, Aachen, Germany

,

Nadia Al-Fakhri^*

²Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps-University, Marburg, Germany

,

Katharina Nemeth

²Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps-University, Marburg, Germany

,

Claudia Goettsch

³Division of Endocrinology,Diabetes, and Bone Diseases, Department of Medicine III, Dresden Technical University Medical Center, Dresden, Germany

,

Leon J. Schurgers

⁴Department of Biochemistry, Cardiovascular Research Institute CARIM, University of Maastricht, Maastricht, The Netherlands

,

Cees Vermeer

⁵VitaK, Cardiovascular Research Institute CARIM, University of Maastricht, Maastricht, The Netherlands

,

Lorenz C. Hofbauer

³Division of Endocrinology,Diabetes, and Bone Diseases, Department of Medicine III, Dresden Technical University Medical Center, Dresden, Germany

,

Michael Schoppet

⁶Department of Internal Medicine and Cardiology, Philipps-University, Marburg, Germany

References
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2 Shanahan CM, Crouthamel MH, Kapustin A. et al. Arterial calcification in chronic kidney disease: key roles for calcium and phosphate. Circ Res 2011; 109: 697-711.
3 Nigwekar SU, Wolf M, Sterns RH. et al. Calciphylaxis from nonuremic causes: a systematic review. Clin J Am Soc Nephrol 2008; 3: 1139-1143.
4 Ketteler M, Bongartz P, Westenfeld R. et al. Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study. Lancet 2003; 361: 827-833.
5 Cranenburg EC, Koos R, Schurgers LJ. et al. Characterisation and potential diagnostic value of circulating matrix Gla protein (MGP) species. Thromb Haemost 2010; 104: 811-822.
6 Cranenburg EC, Vermeer C, Koos R. et al. The circulating inactive form of matrix Gla Protein (ucMGP) as a biomarker for cardiovascular calcification. J Vasc Res 2008; 45: 427-436.
7 Arenas MD, Gil MT, Gutiérrez MD. et al. Management of calcific uremic arteriolopathy (calciphylaxis) with a combination of treatments, including hyperbaric oxygen therapy. Clin Nephrol 2008; 70: 261-264.
8 Hristova M, van Beek C, Schurgers LJ. et al. Rapidly progressive severe vascular calcification sparing the kidney allograft following warfarin initiation. Am J Kidney Dis 2010; 56: 1158-1162.
9 Price PA, Faus SA, Williamson MK. Warfarin-induced artery calcification is accelerated by growth and vitamin D. Arterioscler Thromb Vasc Biol 2000; 20: 317-327.
10 Baldwin C, Farah M, Leung M. et al. Multi-intervention management of calciphylaxis: a report of 7 cases. Am J Kidney Dis 2011; 58: 988-991.

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