Youden’s Index and the Likelihood Ratio Positive in Diagnostic Testing

Summary

We refer to a recent letter to the editor by Hughes [1] and show that, despite existing similarities between Youden’s index and the log-likelihood ratio positive, important differences between these two measures remain to exist which can play an important difference in clinical practice.

Keywords

Youden’s index - likelihood ratio positive - diagnostic testing - Taylor series approximation

• References

• 1 Hughes G. Youden’s index and the Weight of Evidence. Methods Inf Med 2015; 54: 198-199.
• 2 Böhning D, Holling H, Patilea V. A Limitation of the Diagnostic-Odds Ration in Determining an optimal Cut-Off Value for a Continuous Diagnostic Test. Statist Meth Med Res 2011; 20: 541-550.