DOI: 10.1055/s-00000025

Hormone and Metabolic Research

Issue 02/03 · Volume 31 · February 1999 DOI: 10.1055/s-002-6341

Editorial

41
Le Roith, Derek: Insulin-Like Growth Factor

43
Duguay, S. J.: Post-Translational Processing of Insulin-Like Growth Factors
50
Isgaard, J.; Tivesten, Å; Friberg, P.; Bengtsson, B.-Å: The Role of the GH/IGF-I Axis for Cardiac Function and Structure
55
Samuel, D. S.; Ewton, D. Z.; Coolican, S. A.; Petley, T. D.; McWade, F. J.; Florini, J. R.: Raf-1 Activation Stimulates Proliferation and Inhibits IGF-Stimulated Differentiation in L6A1 Myoblasts
65
Lopaczynski, W.; Harris, S.; Nissley, P.: Activation of Extracellular Signal-Regulated Kinases 1 and 2 by Insulin-Like Growth Factor I in Human Osteosarcoma MG-63 Cells
70
Petley, T.; Graff, K.; Jiang, W.; Yang, H.; Florini, J.: Variation Among Cell Types in the Signaling Pathways by which IGF-I Stimulates Specific Cellular Responses*
77
Hänze, J.; Berthold, A.; Klammt, J.; Gallaher, B.; Siebler, T.; Kratzsch, J.; Elmlinger, M.; Kiess, W.: Cloning and Sequencing of the Complete cDNA Encoding the Human Insulin Receptor Related Receptor
80
Prisco, M.; Romano, G.; Peruzzi, F.; Valentinis, B.; Baserga, R.: Insulin and IGF-I Receptors Signaling in Protection from Apoptosis
90
Russell, J. W.; Feldman, E. L.: Insulin-Like Growth Factor-I Prevents Apoptosis in Sympathetic Neurons Exposed to High Glucose
97
Jehle, P. M.; Fussgaenger, R. D.; Blum, W. F.; Angelus, N. K. O.; Hoeflich, A.; Wolf, E.; Jungwirth, R. J.: Differential Autocrine Regulation of Intestine Epithelial Cell Proliferation and Differentiation by Insulin-Like Growth Factor (IGF) System Components
103
MacDonald, R. S.: The Role of Insulin-Like Growth Factors in Small Intestinal Cell Growth and Development
114
Torres-Aleman, I.: Insulin-Like Growth Factors as Mediators of Functional Plasticity in the Adult Brain
120
Anlar, Banu; Sullivan, Kelli A.; Feldman, Eva L.: Insulin-Like Growth Factor-I and Central Nervous System Development
126
León, Yolanda; Sanz, Carmen; Frago, Laura M.; Camarero, Guadalupe; Cañón, Susana; Varela-Nieto, Isabel; Giráldez, Fernando: Involvement of Insulin-Like Growth Factor-I in Inner Ear Organogenesis and Regeneration
133
Prahalada, S.; Block, G.; Handt, L.; DeBurlet, G.; Cahill, M.; Hoe, C. M.; van Zwieten, M. J.: Insulin-Like Growth Factor-1 and Growth Hormone (GH) Levels in Canine Cerebrospinal Fluid are Unaffected by GH or GH Secretagogue (MK-0677) Administration
138
Zumkeller, W.; Schwab, M.: Insulin-Like Growth Factor System in Neuroblastoma Tumorigenesis and Apoptosis: Potential Diagnostic and Therapeutic Perspectives
142
De León, Daisy D.; Issa, Nadia; Nainani, Stephanie; Asmerom, Yayesh: Reversal of Cathepsin D Routing Modulation in MCF-7 Breast Cancer Cells Expressing Antisense Insulin-Like Growth Factor II (IGF-II)
148
Winkler, R.; Delacroix, L.; Bensbaho, K.; Lambert, S.; Collette, J.; Hodzic, D.: IGF-II in Primary Human Colorectal Tumors: Peptide Level, Activated Promoters, Parental Imprinting and Gene Rearrangement
155
Grewal, A.; Bradshaw, S. L.; Schuller, A. G. P.; Low, M. J.; Pintar, J. E.: Expression of IGF System Genes During T-Antigen Driven Pituitary Tumorigenesis
161
Rosenbloom, A. L.: IGF-I Deficiency Due to GH Receptor Deficiency
172
Bereket, A.; Lang, C. H.; Wilson, T. A.: Alterations in the Growth Hormone-Insulin-Like Growth Factor Axis in Insulin Dependent Diabetes Mellitus
182
Lee, C. Y.; Cohen, F. J.; Wu, H.-B.; Ooi, G. T.; Rechler, M. M.: The Absence of 150-kDa Insulin-Like Growth Factor Complexes in Fetal Rat Serum is not Due to a Lack of Functional Acid-Labile Subunit
186
Wu, H.-B.; Lee, C. Young; Rechler, M. M.: Proteolysis of Insulin-Like Growth Factor Binding Protein-3 in Serum from Pregnant, Non-Pregnant and Fetal Rats by Matrix Metalloproteinases and Serine Proteases
192
Ferry, R. J.; Katz, L. E. L.; Grimberg, Adda; Cohen, P.; Weinzimer, S. A.: Cellular Actions of Insulin-Like Growth Factor Binding Proteins
203
Fottner, C.; Engelhardt, D.; Weber, M. M.: Characterization of Insulin-Like Growth Factor Binding Proteins (IGFBPs) Secreted by Bovine Adrenocortical Cells in Primary Culture: Regulation by Insulin-Like Growth Factors (IGFs) and Adrenocorticotropin (ACTH)*
209
Benbassat, C. A.; Lazarus, D. D.; Cichy, S. B.; Evans, T. M.; Moldawer, L. L.; Lowry, S. F.; Unterman, T. G.: Interleukin-1α (IL-1α) and Tumor Necrosis Factor α (TNFα) Regulate Insulin-Like Growth Factor Binding Protein-1 (IGFBP-1) Levels and mRNA Abundance In Vivo and In Vitro*
216
Durham, Susan K.; Suwanichkul, A.; Hayes, J. D.; Herington, A. C.; Powell, D. R.; Campbell, P. G.: The Heparin Binding Domain of Insulin-Like Growth Factor Binding Protein (IGFBP)-3 Increases Susceptibility of IGFBP-3 to Proteolysis
226
Bach, L. A.: Insulin-Like Growth Factor Binding Protein-6: The “Forgotten” Binding Protein?
235
Braulke, T.; Dittmer, F.; Götz, W.; von Figura, K.: Alteration in Pancreatic Immunoreactivity of Insulin-Like Growth Factor (IGF)-Binding Protein (IGFBP)-6 and in Intracellular Degradation of IGFBP-3 in Fibroblasts of IGF-II Receptor/IGF-II-Deficient Mice
242
Braulke, T.: Type-2 IGF Receptor: A Multi-Ligand Binding Protein