DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 03 · Volume 91 · 2004 DOI: 10.1055/s-007-35557

Editorial Focus

416
Lee, Kaeng W.; Lip, Gregory Y. H.: Acute versus habitual exercise, thrombogenesis and exercise intensity
420
Zirlik, Andreas: TAFI: a promising drug target?
423
Preissner, Klaus T.; Machovich, Raymund: Fibrinolysis and proteolysis in a cellular context

Theme Issue Review Article

425
Gils, Ann; Declerck, Paul J.: The structural basis for the pathophysiological relevance of PAI-1 in cardiovascular diseases and the development of potential PAI-1 inhibitors
438
Durand, Michelle K.V.; Bødker, Julie S.; Christensen, Anni; Dupont, Daniel M.; Hansen, Martin; Jensen, Jan K.; Kjelgaard, Signe; Mathiasen, Lisa; Pedersen, Katrine E.; Skeldal, Sune; Wind, Troels; Andreasen, Peter A.: Plasminogen activator inhibitor-1 and tumour growth, invasion, and metastasis
450
Harbeck, Nadia; Kates, Ronald E.; Gauger, Katja; Willems, Amina; Kiechle, Marion; Magdolen, Viktor; Schmitt, Manfred: Urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1: novel tumor-derived factors with a high prognostic and predictive impact in breast cancer
457
Yepes, Manuel; Lawrence, Daniel A.: Neuroserpin: a selective inhibitor of tissue-type plasminogen activator in the central nervous system

Theme Issue Article

465
Epple, Guido; Langfeld, Kristina; Baier, Michael; Holzhütter, Hermann-Georg; Schleuning, Wolf-Dieter; Köttgen, Eckart; Geßner, Reinhard; Praus, Michael: Both lysine-clusters of the NH2-terminal prion-protein fragment PrP23-110 are essential for t-PA mediated plasminogen activation
473
Guimarães, Ana H. C.; Rijken, Dingeman C.: Thrombin activatable fibrinolysis inhibitor (TAFI) affects fibrinolysis in a plasminogen activator concentration-dependent manner
480
Małyszko, Jolanta; Małyszko, Jacek S.; Hryszko, Tomasz; Myśliwiec, Michał: Thrombin activatable fibrinolysis inhibitor (TAFI) and markers of endothelial cell injury in dialyzed patients with diabetic nephropathy
487
Tratar, Gregor; Blinc, Aleš; Štrukelj, Mitja; Mikac, Urša; Serša, Igor: Turbulent axially directed flow of plasma containing rt-PA promotes thrombolysis of non-occlusive whole blood clots in vitro
497
Schoots, Ivo G.; Levi, Marcel; van Vliet, Arlène K.; Declerck, Paul J.; Maas, Adrie M.; van Gulik, Thomas M.: Enhancement of endogenous fibrinolysis does not reduce local fibrin deposition, but modulates inflammation upon intestinal ischemia and reperfusion
506
Kuyvenhoven, Johan Ph.; Molenaar, Quintus I.; Verspaget, Hein W.; Veldman, Marietta G.; Palareti, Gualtiero; Legnani, Cristina; Moolenburgh, Sanne E.; Terpstra, Onno T.; Lamers, Cornelis B.H.W.; van Hoek, Bart; Porte, Robert J.: Plasma MMP–2 and MMP–9 and their inhibitors TIMP-1 and TIMP-2 during human orthotopic liver transplantation
514
Manders, Peggy; Tjan-Heijnen, Vivianne C. G.; Span, Paul N.; Grebenchtchikov, Nicolai; Geurts-Moespot, Anneke J.; van Tienoven, Doorléne T. H.; Beex, Louk V. A. M.; Sweep, Fred C. G. J.: The complex between urokinase-type plasminogen activator (uPA) and its type-1 inhibitor (PAI-1) independently predicts response to first-line endocrine therapy in advanced breast cancer

Blood Coagulation, Fibrinolysis and Cellular Haemostasis

522
Dennis, Michael W.; Downey, Colin; Brufatto, Nicole; Nesheim, Michael E.; Stevenson, Ken; Toh, Cheng Hock: Prothrombinase enhancement through quantitative and qualitative changes affecting very low density lipoprotein in complex with C-reactive protein
531
Gerotziafas, Grigoris T.; Depasse, François; Chakroun, Tahar; Samama, Meyer M.; Elalamy, Ismail: Recombinant factor VIIa partially reverses the inhibitory effect of fondaparinux on thrombin generation after tissue factor activation in platelet rich plasma and whole blood
538
Gatt, Moshe E.; Paltiel, Ora; Bursztyn, Michael: Is prolonged immobilization a risk factor for symptomatic venous thromboembolism in elderly bedridden patients?

Platelets and Blood Cells

544
Kotzailias, Nicole; Finsterer, Josef; Zellner, Maria; Marsik, Claudia; Dukic, Tanja; Jilma, Bernd: Platelet function in mitochondriopathy with stroke and stroke-like episodes
553
Karanikas, Georgios; Zedwitz-Liebenstein, Konstantin; Eidherr, Harald; Schuetz, Matthias; Sauerman, Robert; Dudczak, Robert; Winkler, Stefan; Pabinger, Ingrid; Kletter, Kurt: Platelet kinetics and scintigraphic imaging in thrombocytopenic malaria patients

Wound Healing and Inflammation/Infection

558
Rosenthal, Ann K.; Mosesson, Michael W.; Gohr, Claudia M.; Masuda, Ikuko; Heinkel, David; Seibenlist, Kevin R.: Regulation of transglutaminase activity in articular chondrocytes through thrombin receptor-mediated factor XIII synthesis
569
Hisaka, Toru; Lardeux, Bernard; Lamireau, Thierry; Wüestefeld, Torsten; Lalor, Patricia F.; Neaud, Véronique; Maurel, Patrick; Desmoulière, Alexis; Kisiel, Walter; Trautwein, Christian; Rosenbaum, Jean: Expression of tissue factor pathway inhibitor-2 in murine and human liver regulation during inflammation
576
Guckelberger, Olaf; Sun, Xiao Feng; Sévigny, Jean; Imai, Masato; Kaczmarek, Elzbieta; Enjyoji, Keiichi; Kruskal, Jonathan B.; Robson, Simon C.: Beneficial effects of CD39/ecto-nucleoside triphosphate diphosphohydrolase-1 in murine intestinal ischemia-reperfusion injury
587
Wang, Jong-Shyan; Liao, Chang-Hui: Moderate-intensity exercise suppresses platelet activation and polymorphonuclear leukocyte interaction with surface-adherent platelets under shear flow in men

Endothelium and Vascular Development

595
Raab, Sabine; Beck, Heike; Gaumann, Andreas; Yüce, Ali; Gerber, Hans-Peter; Plate, Karl; Hammes, Hans-Peter; Ferrara, Napoleone; Breier, Georg: Impaired brain angiogenesis and neuronal apoptosis induced by conditional homozygous inactivation of vascular endothelial growth factor

Cell Signaling and Vessel Remodeling

606
Huang, Ping Ping; Li, Shan Zhu; Han, Ming Zhe; Xiao, Zhi Jian; Yang, Ren Chi; Qiu, Lu Gui; Han, Zhong Chao: Autologous transplantation of peripheral blood stem cells as an effective therapeutic approach for severe arteriosclerosis obliterans of lower extremities
610
Schillinger, Martin; Exner, Markus; Mlekusch, Wolfgang; Amighi, Jasmin; Sabeti, Schila; Schlager, Oliver; Wagner, Oswald; Minar, Erich: Serum albumin predicts cardiac adverse events in patients with advanced atherosclerosis – interrelation with traditional cardiovascular risk factors

New Technologies and Diagnostic Tools

619
Mühle, Christiane; Schulz-Drost, Stefan; Khrenov, Alexey V.; Saenko, Evgueni L.; Klinge, Jens; Schneider, Holm: Epitope mapping of polyclonal clotting factor VIII-inhibitory antibodies using phage display

Case Report

626
Krafft, Alexander; Huch, Renate; Hartmann, Sabine; Breymann, Christian: Combined thrombopoietin and platelet response to altitude in a patient with autoimmune thrombocytopenia

Letters to the Editor

628
Konstantoulas, Constantine; Hawe, Emma; Saut, Naomi; Yudkin, John S.; di Minno, Giovanni; Margaglione, Maurizio; Hamsten, Anders; Humphries, Steve E.; Juhan-Vague, Irene; Ireland, Helen; behalf of the HIFMECH Study Group: Common variants in the thrombomodulin gene as a risk for myocardial infarction in the north of Europe (HIFMECH Study)
631
Sepe, Vincenzo; Libetta, Carmelo; Santagostino, Alberto; Rossi, Natalia; Peona, Carlo; Dal Canton, Antonio: Association between platelet annexin-V binding and the occurrence of arteriovenous fistula thrombosis in haemodialyzed patients
632
Quinn, John P.; Murph, Philip T.: Severe intra-abdominal bleeding post liver biopsy – failure to respond to recombinant Factor VII
633
Perzanowski, Christian; Dellweg, Dominic; Eiger, Glenn: Limited use of the SimpliRED assay in confirming pulmonary embolism