DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Ausgabe 07 · Volume 104 · 2010 DOI: 10.1055/s-008-36073

Editorial Focus

1
Weber, Christian: Obstacles and options in the quest for drug candidates against vascular disease

Theme Issue Editorial

4
Tse, Hung-Fat: New era of regenerative medicine for cardiovascular diseases

Theme Issue Article

6
Siu, Chung-Wah; Liao, Song-Yan; Liu, Yuan; Lian, Qizhou; Tse, Hung-Fat: Stem cells for myocardial repair
13
Ransohoff, Katherine J.; Wu, Joseph C.: Advances in cardiovascular molecular imaging for tracking stem cell therapy
23
Boheler, Kenneth R.: Pluripotency of human embryonic and induced pluripotent stem cells for cardiac and vascular regeneration
30
Kong, Chi-Wing; Akar, Fadi G.; Li, Ronald A.: Translational potential of human embryonic and induced pluripotent stem cells for myocardial repair: Insights from experimental models
39
Lian, Qizhou; Chow, Yenyen; Esteban, Miguel Angel; Pei, Duanqing; Tse, Hung-Fat: Future perspective of induced pluripotent stem cells for diagnosis, drug screening and treatment of human diseases

Clinical Focus

45
Karthikeyan, Ganesan; W. Eikelboom, John: The CHADS2 score for stroke risk stratification in atrial fibrillation – friend or foe?

Review Article

49
Ahrens, Ingo; Lip, Gregory Y. H.; Peter, Karlheinz: New oral anticoagulant drugs in cardiovascular disease

Blood Coagulation, Fibrinolysis and Cellular Haemostasis

61
Y. Kim, Paul; E. Nesheim, Michael: Down regulation of prothrombinase by activated protein C during prothrombin activation
Zusatzmaterial
71
Sartori, Michelangelo; Favaretto, Elisabetta; Legnani, Cristina; Cini, Michela; Conti, Eleonora; Amato, Alfio; Palareti, Gualtiero: Thrombophilic risk factors and peripheral arterial disease severity
78
Reitter, Sylvia; Sturn, Rümuth; Horvath, Birgit; Freitag, Renate; Male, Christoph; Muntean, Wolfgang; Streif, Werner; Pabinger, Ingrid; Mannhalter, Christine; and the Austrian Molecular Haemophilia Study Group: Spectrum of causative mutations in patients with haemophilia A in Austria
86
van Doormaal, Frederiek F.; Cohen, Alexander T.; Davidson, Bruce L.; Decousus, Herve; Gallus, Alexander S.; Gent, Michael; Piovella, Franco; Prins, Martin H.; Raskob, Gary E.; Büller, Harry R.: Idraparinux versus standard therapy in the treatment of deep venous thrombosis in cancer patients: A subgroup analysis of the Van Gogh DVT trial
92
Traby, Ludwig; Kaider, Alexandra; Schmid, Rainer; Kranz, Alexander; Quehenberger, Peter; Kyrle, Paul A.; Eichinger, Sabine: The effects of low-molecular-weight heparin at two different dosages on thrombin generation in cancer patients.
100
Folsom, Aaron R.; Lutsey, Pamela L.; Heckbert, Susan R.; Cushman, Mary: Serum albumin and risk of venous thromboembolism
105
Nishiya, Katsumi; Nogami, Keiji; Okada, Kiyotaka; Matsuo, Osamu; Takeyama, Masahiro; Ogiwara, Kenichi; Shima, Midori: Determination of a factor VIII-interactive region within plasmin responsible for plasmin-catalysed activation and inactivation of factor VIII(a)
118
Crowther, Mark A.; Garcia, David; Ageno, Walter; Wang, Luqi; Witt, Dan M.; Clark, Nathan P.; Blostein, Mark D.; Kahn, Susan R.; Schulman, Sam; Kovacs, Michael; Rodger, Marc A.; Wells, Philip; Anderson, David; Ginsberg, Jeffrey; Selby, Rita; Siragusa, Sergio; Silingardi, Mauro; Dowd, MaryBeth B.; Kearon, Clive: Oral vitamin K effectively treats international normalised ratio (INR) values in excess of 10

Cardiovascular Biology and Cell Signalling

122
Kaireviciute, Diana; D. Blann, Andrew; Balakrishnan, Balu; Lane, Deirdre A.; Patel, Jeetesh V.; Uzdavinys, Giedrius; Norkunas, Gediminas; Kalinauskas, Gintaras; Sirvydis, Vytautas; Aidietis, Audrius; Lip, Gregory Y. H.: Characterisation and validity of inflammatory biomarkers in the prediction of post-operative atrial fibrillation in coronary artery disease patients
128
Barrabés, José A.; Inserte, Javier; Mirabet, Maribel; Quiroga, Adoración; Hernando, Víctor; Figueras, Jaume; Garcia-Dorado, David: Antagonism of P2Y12 or GPIIb/IIIa receptors reduces platelet-mediated myocardial injury after ischaemia and reperfusion in isolated rat hearts
136
Loubele, Sarah T. B. G.; Cate, Hugo ten; Spronk, Henri M. H.: Anticoagulant therapy in critical organ ischaemia/reperfusion injury
143
Bai, Lili; Gabriels, Karen; Wijnands, Erwin; Rousch, Mat; Daemen, Mat J. A. P.; Cohen Tervaert, J. W.; Biessen, Erik A. L.; Heeneman, Sylvia: Low- but not high-dose FK506 treatment confers atheroprotection due to alternative macrophage activation and unaffected cholesterol levels
Zusatzmaterial
151
Cella, Giuseppe; Marchetti, Marina; Vianello, Fabrizio; Panova-Noeva, Marina; Vignoli, Alfonso; Russo, Laura; Barbui, Tiziano; Falanga, Anna: Nitric oxide derivatives and soluble plasma selectins in patients with myeloproliferative neoplasms

Animal Models

157
Johansen, Peter B.; Bjørn, Søren E.; Agersø, Henrik; Thorup, Inger; Hermit, Mette B.; Sørensen, Brit B.; Stennicke, Henning R.; Ezban, Mirella; Tranholm, Mikael: Prolonged effect of GlycoPEGylated rFVIIa (40k-PEG-rFVIIa) in rabbits correlates to activity in plasma
165
Van Hul, Matthias; Piccard, Heléne; Lijnen, H. Roger: Gelatinase B (MMP-9) deficiency does not affect murine adipose tissue development

New Technologies, Diagnostic Tools and Drugs

172
Derkach, Dmitry N.; Wadekar, Subhagya A.; Perkins, Kim B.; Rousseau, Emma; Dreiza, Catherine M.; Cheung-Flynn, Joyce; Ramos, Heidi C.; Ugarova, Tatiana P.; Sheller, Michael R.: RGD-dependent binding of TP508 to integrin αvβ3 mediates cell adhesion and induction of nitric oxide

Letters to the Editor

183
Sierko, Ewa; Wojtukiewicz, Marek Z.; Ostrowska-Cichocka, Krystyna; Zimnoch, Lech: Protein Z-dependent protease inhibitor (ZPI) is present in loco in human breast cancer tissue
186
Bhagat, Ramesh; Sharma, Kapil; Sarode, Ravi; Shen, Yu-Min: Delayed massive pulmonary thromboembolic phenomenon following envenomation by Mojave rattlesnake (Crotalus scutulatus)
189
A. Klok, Frederikus; van der Bijl, Noortje; Mos, Inge C. M.; de Roos, Albert; Kroft, Lucia J. M.; Huisman, Menno V.: Timing of NT-pro-BNP sampling for predicting adverse outcome after acute pulmonary embolism