32. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung
Wilsede,
05.–07.06.2019
Wissenschaftliche Leitung: Prof. Dr. Jan-Henning Klusmann, Martin-Luther-Univsersität Halle-Wittenberg Prof. Dr. Martin Stanulla, Medizinische Hochschule Hannover Prof. Dr. Rolf Marschalek, Goethe-Universität, Frankfurt (Main) Prof. Dr. Olaf Heidenreich, Prinses Máxima Centrum voor Kinderoncologie, Utrecht, Niederlande
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Zanetti, SR;
Velazco-Hernandez, T;
Gutierrez-Agüera, F;
Roca-Ho, H;
Sánchez-Martínez, D;
Petazzi, P;
Torres, R;
Molina, O;
Torrebadell-Burriel, M;
Vidriales-Vicente, MB;
Hrusak, O;
Fuster, JL;
Juan, M;
Bueno, C;
Menéndez, P:
CD19 and CD22-directed biespecific CAR for B-cell Acute Lymphoblastic Leukemia
FREE ACCESS
2
Molina, O;
Bueno, C;
Bosch, A;
Granada, I;
Roca-Ho, H;
Gutierrez-Agüera, F;
Tirados, S;
Pal, D;
Ballerini, P;
deBoer, M;
Plensa, I;
Calasanz, MJ;
Rodríguez, R;
Camos, M;
Calvo, M;
Menendez, P:
Chromosome structure and mitotic defects are major pathogenic mechanisms in hyperdiploid childhood B-ALL
FREE ACCESS
3
Torres-Ruiz, R;
Bueno, C;
Velasco-Hernandez, T;
Roca-Ho, H;
Gutierrez-Aguera, F;
Quintana, O;
Segovia, JC;
Roy, A;
Rodriguez-Perales, S;
Menendez, P:
CRISPR-mediated genome editing of t(4;11) in human prenatal and perinatal hematopoietic stem/progenitor cells
FREE ACCESS
4
Bueno, C;
Tejedor, JR;
Bashford-Rogers, R;
Gonzalez Silva, L;
Valdés-Mas, R;
Fraga, MF;
Fernandez, A;
Ballerini, P;
Varela, I;
Menendez, P:
Evolutionary trajectories and cell-of-origin of TCF3-ZNF384&PTPN11 mutations in monozygotic twins with concordant B-ALL
FREE ACCESS
5
Tauchmann, S;
Almosailleakh, M;
Leonards, K;
Otzen Bagger, F;
Juge, S;
Thirant, C;
Méreau, H;
Peters, AHFM;
Mercher, T;
Schwaller, J:
Inactivation of Nsd1 impairs terminal erythroid maturation and induces erythroleukemia
FREE ACCESS
17
Weiss, JM;
Mittapalli, VM;
Molnar, C;
Schmitt, I;
Andrieux, G;
Gonzalez, I;
Börries, M;
Quintanilla-Martinez, L;
Niemeyer, CM;
Erlacher, M:
Too little is too much: Leukemogenesis in the Gata2 syndrome
FREE ACCESS
30
Hinze, L;
Pfirrmann, M;
Karim, S;
Degar, J;
Bauer, DE;
Gregory, RI;
Stanulla, M;
Wagner, F;
Stegmaier, K;
Gutierrez, A:
Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias
FREE ACCESS
34
Müller, J;
Fedders, B;
Cario, G;
Schrappe, M;
Schewe, D;
Möricke, A;
Lilljebjörn, H;
Fioretos, T;
Zimmermann, M;
Stanulla, M:
Stratification and prognosis of IGH-DUX4 positive acute lymphoblastic leukemia in children
FREE ACCESS
35
Spory, L;
Lenk, L;
Winterberg, D;
Alsadeq, A;
Carlet, M;
Jeremias, I;
Cario, G;
Schrappe, M;
Vossen-Gajcy, M;
Schewe, DM:
FOS and FOSB are linked with CNS-infiltration and inferior prognosis in childhood T-cell acute lymphoblastic leukemia
FREE ACCESS
36
Heymann, J;
Vogiatzi, F;
Rösner, T;
Lenk, L;
Cario, G;
Schrappe, M;
Valerius, T;
Peipp, M;
Kellner, C;
Schewe, DM:
Venetoclax enhances the efficacy of therapeutic antibodies in B-cell malignancies
FREE ACCESS
45
Szoltysek, K;
Dormon, K;
Blair, H;
Tirtakusuma, R;
Dodd, C;
Law, E;
Nakjang, S;
Pal, D;
Vormoor, J;
Heidenreich, O:
Genome-wide CRISPR screen in patient derived cells reveals the mechanism of ALL chemoresistance
FREE ACCESS
46
Tirtakusuma, R;
Milne, P;
Ptasinska, A;
Williamson, D;
Blair, H;
Meyer, C;
Marschalek, R;
Bonifer, C;
Bomken, S;
Heidenreich, O:
Genomic characterisation of lineage switched MLL-rearranged leukemias
FREE ACCESS
47
Ritter, MU;
Klimenkova, O;
Klimiankou, M;
Schmidt, A;
Stocking, C;
Kanz, L;
Zeidler, C;
Link, DC;
Welte, K;
Skokowa, J:
Downstream effect of CSF3R and RUNX1 mutations that underlie leukemic transformations in congenital neutropenia (CN)
FREE ACCESS
48
Nasri, M;
Dannenmann, B;
Ritter, M;
Mir, P;
Xu, Y;
Klimiankou, M;
Zeidler, C;
Kanz, L;
Welte, K;
Skokowa, J:
CRISPR/Cas9 Gene-modification Platform of ELANE Mutations in iPSCs and HSPCs of Severe Congenital Neutropenia Patients
FREE ACCESS
49
Dannenmann, B;
Klimiankou, M;
Mardan, J;
Oswald, B;
Solovyeva, A;
Ritter, M;
Kanz, L;
Zeidler, C;
Welte, K;
Skokowa, J:
iPSC Model of Stepwise Leukemia Development in Congenital Neutropenia Reveals BAALC as a Key Mediator of Leukemogenesis
FREE ACCESS
50
Mir, P;
Klimiankou, M;
Nasri, M;
Dannenmann, B;
Findik, B;
Rieger, M;
Kanz, L;
Zeidler, C;
Welte, K;
Skokowa, J:
GADD45b plays an essential role in the G-CSF triggered granulocytic differentiation of human hematopoietic cells
FREE ACCESS
51
Morishima, T;
Krahl, AC;
Xu, Y;
Aghaallaei, N;
Nasri, M;
Findik, B;
Bajoghli, B;
Müller, P;
Welte, K;
Skokowa, J:
NAMPT-mediated LMO2 deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis
FREE ACCESS
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Gerber, T;
Taschner-Mandl, S;
Buder, A;
Saloberger, L;
Berneder, M;
Brunner-Herglotz, B;
Ziegler, A;
Ladenstein, R;
Ambros, IM;
Ambros, PF:
Liquid biopsy in neuroblastoma: cfDNA analysis for sensitive follow-up monitoring and early relapse detection
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