Synlett

Issue 01 · January 2026

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Synpacts
1
Wang, Lei; Peng, Xianglu; Wang, Gang-Wei:
Dynamic Kinetic Activation of Aziridines to Access Azepines

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12
Qiqige, Qiqige; Wang, Zhaobin:
Unlocking the Potential of Less-Stabilized Carbenes in Chemical Synthesis: Chromium-Catalyzed Asymmetric Cyclopropanation

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19
Pal, Giriraj; Voigtländer, Maximilian; Tzaras, Dimitrios-Ioannis; Gorai, Mahadeb; Teichert, Johannes F.:
Enhancing Reactivity and Selectivity of H₂-driven Copper Hydride Chemistry with Bifunctional N-heterocyclic Carbene Ligands Bearing Basic Subunits

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Account
Published as part of the Cluster Alkynes in Organic Synthesis
25
Srinivas, Dasari; Dakoju, Ravi Kishore; Chinnabattigalla, Sreenivasulu; Satyanarayana, Gedu:
Alkyne-Based Cascade Strategies for the Construction of Diverse Carbo/Heterocycles

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Published as part of the Special Section 15th EuCheMS Organic Division Young Investigator Workshop
43
Pieber, Bartholomäus:
Photochemical Cross-Couplings using Semiconducting Materials

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55
Xu, Shibo; Hirano, Koji:
Pd- and Photo-Promoted C−H Functionalizations of Phospholes

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67
Prabha, Shashi; Rajput, Sobhit Singh:
Exploring Chalcone Derivatives Against Alzheimer’s Disease: Biological Activity and Structure–Activity Relationships

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Perspectives
Published as part of the Cluster Alkynes in Organic Synthesis
76
Beil, Sebastian B.:
Tetraethynylmethane: A Quest for the “Dutch Diamond”

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Letter
81
Vasylyshyn, Roman Y.; Demydchuk, Bohdan A.; Kovalenko, Sergiy M.; Matiychuk, Vasyl S.; Shishkina, Svetlana; Lukin, Oleg; Karpun, Yevhen; Shivanyuk, Alexander; Fetyukhin, Volodymyr M.:
Practical One-Pot Four-Step Synthesis of Isocoumarin-3-Carboxylic Acids

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Published as part of the Special Issue dedicated to Prof. S. Chandrasekaran on his 80th birthday
86
Pratihar, Subhamoy; Kuilya, Debajyoti; Qasim, Md; Das, Arnab; Sinha, Surajit:
Pseudouridine-Modified Phosphorodiamidate Morpholino Oligonucleotides: Synthesis and Biophysical Insights

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91
Iwamoto, Ryo; Suga, Takuya; Soeta, Takahiro; Ukaji, Yutaka:
Synthesis of Azetidine Nitrones by Double Methylene Incorporation into Nitrile Oxides Using Diazomethane

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95
Ahire, Milind M.; Belani, Jitendra D.:
Enaminone-Directed Rh(III)-Catalyzed Hydroarylation Reaction of Oxa/azabenzonorbornadienes through C–H Bond Functionalization

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99
Li, Jing; Li, Shuangshuang; Gao, Mengyu:
Bis(acetoxy)iodobenzene-Mediated Direct Transformation of α-Amino Acids into Nitriles

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Published as part of the Special Issue dedicated to Prof. S. Chandrasekaran on his 80th birthday
103
Saeed, Shireen Aaisha; Khan, Faiz Ahmed:
Total Synthesis of (±) Pimeforazine A and B

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108
Ghous, Faraz; Kirubakaran, Sivapriya:
Developing New Pyrido[2,3-d]pyrimidine-Based Small Molecules as Potent ATR Inhibitors

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117
Ghosh, Arun K.; McDonald, Tristan John:
TiCl₄-Promoted Intramolecular Friedel–Crafts Cyclization of α-Keto-phenylbutanoates: Synthesis of Substituted Indane and Indene Derivatives

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123
Ramisetty, Mohana Krishna; Yadav, Vikas; Venkitasamy, Kesavan; Baskaran, Sundarababu:
Exploration of Oxetanes and Azetidines in Structure-Based Drug Design

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135
Jadhav, Pramod M.; Jamdade, Akash Bandu; Gnanaprakasam, Boopathy:
Ru-Catalyzed Domino C-4 Alkylation and Hydroxylation of Pyrazolones Using Alcohols via Borrowing-Hydrogen Catalysis

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Correction
e1
Vasylyshyn, Roman Y.; Demydchuk, Bohdan A.; Kovalenko, Sergiy M.; Matiychuk, Vasyl S.; Shishkina, Svetlana; Lukin, Oleg; Karpun, Yevhen; Shivanyuk, Alexander; Fetyukhin, Volodymyr M.:
Correction: Practical One-Pot Four-Step Synthesis of Isocoumarin-3-Carboxylic Acids

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