Facial Plast Surg 2023; 39(06): 686-690
DOI: 10.1055/a-1920-0876
Original Research

Are Antibiotics Needed in Septorhinoplasty? An Evidence-Based Approach

1   Department of Otolaryngology, Lewisham and Greenwich National Health Services Trust Ringgold Standard Institution, London, United Kingdom of Great Britain and Northern Ireland
,
Konstantinos Argiris
2   Department of Ear, Nose and Throat Surgery, Lewisham Hospital National Health Services Trust Ringgold Standard Institution, London, United Kingdom of Great Britain and Northern Ireland
,
1   Department of Otolaryngology, Lewisham and Greenwich National Health Services Trust Ringgold Standard Institution, London, United Kingdom of Great Britain and Northern Ireland
,
Alwyn Ray D'Souza
1   Department of Otolaryngology, Lewisham and Greenwich National Health Services Trust Ringgold Standard Institution, London, United Kingdom of Great Britain and Northern Ireland
› Institutsangaben

Abstract

The use of prophylactic antibiotics in the context of septorhinoplasty (SRP) is a frequently debated topic among plastic surgeons. Most surgeons routinely use antibiotics to prevent the dreaded physical and psychological morbidity of postoperative infections, although this practice is controversial. With antimicrobial resistance becoming a global threat, however, optimizing antibiotic prescribing is essential. The current evidence would suggest that the rate of postoperative infection is low and routine antibiotic use is unnecessary in SRP surgery. Rates range from 0.5 to 2% in simple SRP surgery, majority of which are minor nasal infections which respond to oral antibiotics and do not require hospital admission. In cases of complex SRP, defined as revision cases or where grafts or implants have been utilized, infection rates can be much higher with an incidence of 7 to 11%, and as such utilization of antibiotics is reasonable. When considering the regime to be utilized, a single preoperative dose of intravenous antibiotics has the same efficacy in reducing the incident of postoperative infection as a postoperative 7-day course of oral antibiotics. In the authors' practice, all patients receive a single intravenous dose of antibiotics on induction, and in the case of utilization of a graft from a nonnasal site, this is complimented with an oral course of postoperative antibiotics. With this approach, infections rates are at the lowest range of available published literature.



Publikationsverlauf

Accepted Manuscript online:
05. August 2022

Artikel online veröffentlicht:
03. Dezember 2022

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  • References

  • 1 Georgiou I, Farber N, Mendes D, Winkler E. The role of antibiotics in rhinoplasty and septoplasty: a literature review. Rhinology 2008; 46 (04) 267-270
  • 2 Yoo DB, Peng GL, Azizzadeh B, Nassif PS. Microbiology and antibiotic prophylaxis in rhinoplasty: a review of 363 consecutive cases. JAMA Facial Plast Surg 2015; 17 (01) 23-27
  • 3 Glück U, Gebbers JO. The nose as bacterial reservoir: important differences between the vestibule and cavity. Laryngoscope 2000; 110 (3, pt. 1): 426-428
  • 4 Angelos PC, Wang TD. Methicillin-resistant Staphylococcus aureus infection in septorhinoplasty. Laryngoscope 2010; 120 (07) 1309-1311
  • 5 Abuzeid WM, Brandt MG, Moyer JS, Baker SR. Methicillin-resistant Staphylococcus aureus-associated infections following septorhinoplasty. Facial Plast Surg 2012; 28 (03) 354-357
  • 6 Rajan GP, Fergie N, Fischer U, Romer M, Radivojevic V, Hee GK. Antibiotic prophylaxis in septorhinoplasty? A prospective, randomized study. Plast Reconstr Surg 2005; 116 (07) 1995-1998
  • 7 González-Castro J, Lighthall JG. Antibiotic use in facial plastic surgery. Facial Plast Surg Clin North Am 2016; 24 (03) 347-356
  • 8 Ariyan S, Martin J, Lal A. et al. Antibiotic prophylaxis for preventing surgical-site infection in plastic surgery: an evidence-based consensus conference statement from the American Association of Plastic Surgeons. Plast Reconstr Surg 2015; 135 (06) 1723-1739
  • 9 Beck DO, Kenkel JM. Evidence-based medicine: rhinoplasty. Plast Reconstr Surg 2014; 134 (06) 1356-1371
  • 10 Yoder MG, Weimert TA. Antibiotics and topical surgical preparation solution in septal surgery. Otolaryngol Head Neck Surg 1992; 106 (03) 243-244
  • 11 Weimert TA, Yoder MG. Antibiotics and nasal surgery. Laryngoscope 1980; 90 (04) 667-672
  • 12 Ishii LE, Tollefson TT, Basura GJ. et al. Clinical practice guideline. Improving nasal form and function after rhinoplasty executive summary. Otolaryngol Head Neck Surg 2017; 156 (02) 205-219
  • 13 Scottish Intercollegiate Guidelines Network (SIGN) 104. Antibiotic prophylaxis in surgery. Accessed August 14, 2022 at: http://medicinainterna.net.pe/images/guias/GUIA_PARA_LA_PROFILAXIS_ANTIBIOTICA_EN_CIRUGIA.pdf
  • 14 Kullar R, Frisenda J, Nassif PS. The more the merrier? Should antibiotics be used for rhinoplasty and septorhinoplasty?-a review. Plast Reconstr Surg Glob Open 2018; 6 (10) e1972
  • 15 Lee JH, Sherris DA, Moore EJ. Combined open septorhinoplasty and functional endoscopic sinus surgery. Otolaryngol Head Neck Surg 2005; 133 (03) 436-440
  • 16 McGraw-Wall B, MacGregor AR. Concurrent functional endoscopic sinus surgery and rhinoplasty: pros. Facial Plast Surg Clin North Am 2004; 12 (04) 425-429 , vi
  • 17 Andrews PJ, East CA, Jayaraj SM, Badia L, Panagamuwa C, Harding L. Prophylactic vs postoperative antibiotic use in complex septorhinoplasty surgery: a prospective, randomized, single-blind trial comparing efficacy. Arch Facial Plast Surg 2006; 8 (02) 84-87
  • 18 Nuyen B, Kandathil CK, Laimi K, Rudy SF, Most SP, Saltychev M. Evaluation of antibiotic prophylaxis in rhinoplasty: a systematic review and meta-analysis. JAMA Facial Plast Surg 2019; 21 (01) 12-17
  • 19 Okur E, Yildirim I, Aral M, Ciragil P, Kiliç MA, Gul M. Bacteremia during open septorhinoplasty. Am J Rhinol 2006; 20 (01) 36-39
  • 20 Slavin SA, Rees TD, Guy CL, Goldwyn RM. An investigation of bacteremia during rhinoplasty. Plast Reconstr Surg 1983; 71 (02) 196-198
  • 21 Rettinger G. Risks and complications in rhinoplasty. GMS Curr Top Otorhinolaryngol Head Neck Surg 2007; 6: Doc08
  • 22 Thumfart WF, Völklein C. Systemic and other complications. Facial Plast Surg 1997; 13 (01) 61-69
  • 23 Bremond D, Cauchois R, Gignac D. Acute post-rhinoplasty dacryocystitis. Apropos of a case [in French]. Rev Stomatol Chir Maxillofac 1994; 95 (03) 222-225
  • 24 Flowers RS, Anderson R. Injury to the lacrimal apparatus during rhinoplasty. Plast Reconstr Surg 1968; 42 (06) 577-581
  • 25 Holt GR, Garner ET, McLarey D. Postoperative sequelae and complications of rhinoplasty. Otolaryngol Clin North Am 1987; 20 (04) 853-876
  • 26 Casaubon JN, Dion MA. Labrisseau. Septic cavernous sinus thrombosis after rhinoplasty: a case report. Plast Reconstr Surg 1977; 122 (06) 923-925
  • 27 Layliev J, Gupta V, Kaoutzanis C. et al. Incidence and preoperatice risk factors for major complications in aesthetic rhinoplasty: Analysis of 4978 patients. Aesthet Surg J 2017; 37 (07) 757-767