Epigenetische Veränderungen in Zusammenhang mit Bewegungstherapie

Zusammenfassung

Zahlreiche Studien belegen: Wer Sport treibt, reduziert sein Risiko für Diabetes, Herz-Kreislauf-Erkrankungen und bestimmte Arten von Krebs. Neben den unmittelbaren Effekten auf Muskeln und Gefäße haben Bewegung und Sport auch einen direkten Einfluss auf epigenetische Prozesse, die zu einer veränderten Genregulation führen. Das bedeutet auch, dass epigenetische Signaturen als molekularer Nachweis von Sport und Bewegung genutzt werden können. Dazu dienen heutzutage nicht-invasive Methoden auf Basis von Speichel oder Fingerkuppenblut, um bewegungstherapeutische Effekte zu analysieren und individuell zu steuern. Das hat zur Folge, dass molekular-basierte und personalisierte Therapiekonzepte einfacher realisierbar werden.

Summary

Numerous studies have shown that people who exercise reduce their risk of diabetes, cardiovascular disease and certain types of cancer. In addition to the direct effects on muscles and blood vessels, exercise and sport also have a direct influence on epigenetic processes that lead to altered gene regulation. This also means that epigenetic signatures can be used as molecular evidence of sport and exercise. Nowadays, non-invasive methods based on saliva or fingertip blood are used to analyse movement therapy effects and to control them individually. As a result, molecular-based and personalized therapy concepts become easier to implement.

Stichworte

Epigenetik - Chromatin - Histone - molekulare Bewegungstherapie

Key words

Epigenetics - chromatin - histones - molecular exercise therapy

Publication History

Received: 20 April 2023

Accepted after revision: 24 May 2023

Article published online:
07 August 2023

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