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Zeitschrift für Orthomolekulare Medizin 2024; 22(01): 11-18
DOI: 10.1055/a-2260-1800
Wissen

Selenoprotein P – die Drehscheibe im Selenstoffwechsel

Günther Stoll
,
Uwe Gröber
,
Lutz Schomburg
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Zusammenfassung

Selen ist ein essenzielles Spurenelement, das im Körper in Form von Selenoproteinen verschiedene physiologische Funktionen erfüllt. Die Hauptform des Selens im Blutplasma ist das Selenoprotein P (SELENOP). Neben seiner Funktion als wichtigster Transporter im Körper übernimmt es auch Speicher- und Verteilerfunktionen. Eine niedrige Konzentration an SELENOP wurde als Risikofaktor für eine Reihe verschiedener Erkrankungen und generell mit verringerter Lebenserwartung assoziiert. Auch beim Selenmangel gibt es einige Gesundheitsrisiken. Der Ausgleich eines Selendefizits ist relativ einfach und kann durch eine bessere Versorgung erfolgen.

Schlüsselwörter

Selen - Selenoproteine - SELENOP - Selenmangel


Publication History

Article published online:
11 April 2024

© 2024. Thieme. All rights reserved.

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