Download PDF
Synthesis
DOI: 10.1055/a-2343-0780
review

Directing Group Assisted Transition Metal Catalyzed Selective BH Functionalization of o-Carboranes

Jie Zhang
1   Chemistry, The Chinese University of Hong Kong, Hong Kong, Hong Kong (Ringgold ID: RIN26451)
,
Zuowei Xie
2   Chemistry, Southern University of Science and Technology, Shenzhen, China (Ringgold ID: RIN255310)
› Author AffiliationsSupported by: National Natural Science Foundation of China 22331005
Supported by: Research Grants Council, University Grants Committee 14305420
Supported by: Shenzhen Science and Technology Program QTD20221101093558015
› Further Information
  PDF Download All articles of this category

Carboranes are a type of molecular clusters consisting of carbon, hydrogen and boron atoms. They possess unique characteristics such as three-dimensional aromaticity, icosahedral geometry, and robustness. Functionalized carboranes have been utilized in various fields including medicine, materials, and organometallic/coordination chemistry. In this context, selective functionalization of o-carboranes has received tremendous attention, specifically in the regio- and enantio-selective modification of the ten chemically similar BH vertices within the carborane cage. In recent years, significant progress has been made in catalytic vertex-specific BH functionalization, as well as achieving enantioselective functionalization of the cage BH. This review provides an overview of the recent advancements in this research field.



Publication History

Received: 06 May 2024

Accepted after revision: 11 June 2024

Accepted Manuscript online:
11 June 2024

© . Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany