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Synthesis
DOI: 10.1055/a-2349-6836
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Iron(III)-Catalysed Povarov Cyclisation for the Synthesis of Fused Dibenzo-[b,f] [1,7]-Naphthyridines Embedded Arylpyrrolo Scaffolds

Umasish Jana 
1   Department of Chemistry, Jadavpur University, Kolkata, India
,
Rajkamal Sahoo
2   Department of Chemistry, Jadavpur University, Kolkata, India
,
Abhishek Kar
3   Department of Chemistry, Jadavpur University, Kolkata, India
,
Gopal Rana
4   Department of Chemistry, Jadavpur University, Kolkata, India
,
Sourav Ghosh
5   Department of Chemistry, Jadavpur University, Kolkata, India
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An FeCl3 catalyzed Povarov reaction for the efficient synthesis of dibenzo[b,f]-[1,7]-naphthyridines utilizing 2-pyrolecarbaldehyde-2`-alkynylaryl and aryl amine in excellent yields. The essential features of the present strategy are; easy preparation of substrates, broad substrate scope, mild reaction conditions, high atom economy and yields in the presence of environmentally friendly iron catalysis.



Publication History

Received: 11 May 2024

Accepted after revision: 20 June 2024

Accepted Manuscript online:
20 June 2024

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