Nuklearmedizin
DOI: 10.1055/a-2383-2527
Case Report

A Case of Thoracic SMARCA4-Deficient Undifferentiated Tumor on 18F-FDG PET/CT

Gege Zhao
1   Nuclear Medicine, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China (Ringgold ID: RIN56660)
,
Zhongke Huang
1   Nuclear Medicine, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China (Ringgold ID: RIN56660)
› Author Affiliations

Abstract

A 65-year-old man, who denied a smoking history, presented with chest distress and pain persisting for over a week. A contrast-enhanced chest CT scan revealed a large irregular mass in the right thoracic cavity with heterogeneous enhancement. The 18F-FDG PET/CT showed a large mass in the right thoracic cavity with heterogeneous markedly high FDG uptake. The patient subsequently underwent a bronchoscopic-guided mucosal biopsy at the opening of the right upper lobe. The histological and immunohistochemical findings were consistent with thoracic SMARCA4-deficient undifferentiated tumor.



Publication History

Received: 31 July 2024

Accepted: 06 August 2024

Article published online:
20 November 2024

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