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Synthesis
DOI: 10.1055/a-2464-8904
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A photocatalytic C(sp)ꟷB bond formation employing SOMOphilic alkynyl sulfones and nucleophilic boryl radicals

Enrique M. Arpa 
1   Organic Chemistry, RWTH Aachen University, Aachen, Germany (Ringgold ID: RIN9165)
,
Eva Rivera-Chao
1   Organic Chemistry, RWTH Aachen University, Aachen, Germany (Ringgold ID: RIN9165)
,
Luka Obradović
1   Organic Chemistry, RWTH Aachen University, Aachen, Germany (Ringgold ID: RIN9165)
,
Javier Corpas 
1   Organic Chemistry, RWTH Aachen University, Aachen, Germany (Ringgold ID: RIN9165)
› Author AffiliationsSupported by: H2020 Marie Skłodowska-Curie Actions 101104383
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Alkynylboron compounds are important scaffolds with broad applicability in Organic Synthesis. In contrast to polar or metal-catalyzed processes, here we employ a radical approach for the addition of nucleophilic boryl radicals to electrophilic SOMOphiles for the construction of the C(sp)ꟷB bond. The reaction renders the corresponding alkynylated amine boranes with broad functional group compatibility. In addition, we carried out theoretical studies by means of DFT to understand the reactivity and selectivity of the addition process.



Publication History

Received: 26 September 2024

Accepted after revision: 08 November 2024

Accepted Manuscript online:
08 November 2024

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