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Synlett
DOI: 10.1055/a-2807-2860
Letter

Transfer Hydrogenation of Quinolines Catalyzed by Novel Cyclic Phosphorodiamidic Acid

Authors

  • Shilong Tian 

    1   School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, China (Ringgold ID: RIN12676)

  • Jiawen Xiong

    1   School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, China (Ringgold ID: RIN12676)

  • Min Zhang

    1   School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, China (Ringgold ID: RIN12676)

  • Ting Zhao

    1   School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, China (Ringgold ID: RIN12676)

  • Panpan Yue

    1   School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, China (Ringgold ID: RIN12676)

  • Liuqing Yang

    1   School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, China (Ringgold ID: RIN12676)

  • Peng Liu 

    1   School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, China (Ringgold ID: RIN12676)

Supported by: Natural Science Foundation of Jiangsu Province BK20240836
Supported by: Senior Talent Research Startup Funding of Jiangsu University 5501310017
Further Information
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Cyclic phosphorodiamidic acid is easy to be synthesized and used as Brønsted acid to catalyze hydrogenation of quinolines. The reaction conditions are mild and substrates scope is wide with high yield. Several applications of this method have been realized, especially enantioselective synthesis with moderate result.



Publication History

Received: 02 December 2025

Accepted after revision: 05 February 2026

Accepted Manuscript online:
05 February 2026

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