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Horm Metab Res 1970; 2(5): 271-274
DOI: 10.1055/s-0028-1096814
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© Georg Thieme Verlag KG Stuttgart · New York

Effect of Diabetes on the Uptake of Radioactive Sulphate Into Chondroitin Sulphate by Rat Liver Soluble Enzyme

M. P. Cohen , J.  Bluguermann , V. G. Foglia
  • Institute of Physiology, University of Buenos Aires, Buenos Aires, Argentina
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Publication Date:
08 January 2009 (online)

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Abstract

The uptake of radioactive sulphate into chondroitin sulphate catalyzed by the hepatic enzyme system of normal and pancreatectomized diabetic male rats was examined. It was found that the enzymatic uptake of Iabeled sulphate into chondroitin sulphate was stimulated with low concentrations (less than 1.0 mg) of soluble enzyme prepared from livers of diabetic rats, whereas high concentrations (greater than 2.0 mg) of diabetic enzyme protein non-competitively inhibited radioactive sulphate uptake.

Key words

Chondroitin Sulphate - Pancreatectomy in Rats