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Planta Med 1978; 34(7): 299-304
DOI: 10.1055/s-0028-1097455
DOI: 10.1055/s-0028-1097455
Research Articles
© Georg Thieme Verlag Stuttgart · New York
Helenalinmethacrylate, a new Pseudoguaianolide from the Flowers of Arnica montana L. and the sensitizing Capacity of their Sesquiterpene Lactones
Further Information
Publication History
Publication Date:
13 January 2009 (online)
Abstract
Helenalinmethacrylate, a new ester from helenalin, and helenalinacetate were isolated from the flowers of Arnica montana. L. (Asteraceae). The structure of helenalinmethacrylate was established. Based on sensitizing experiments in guinea pigs helenalin, isolated from the flowers of A. longifolia, and helenalinacetate must be considered as contact allergens. Helenalinacetate and helenalinmethacrylate could be considered as sensitizers for the often observed allergic contact dermatitis caused by the flowers of A. montana and the „Tinctura Arnicae”.
Key Word Index
Arnica montana L - Asteraceae - New Pseudoguaianolide: Helenalinmethacrylate - Contact Allergens - Helenalinacetate - Helenalin