The TSH Receptor in Autoimmune Basedow's Disease

T. Akamizu; M. Saji; S. Ikuyama; S. Kosugi; K. Tahara; L. D. Kohn

doi:10.1055/s-0029-1211055

Experimental and Clinical Endocrinology & Diabetes, Inhaltsverzeichnis

Exp Clin Endocrinol Diabetes 1991; 97(2/03): 153-159
DOI: 10.1055/s-0029-1211055

Original

The TSH Receptor in Autoimmune Basedow's Disease

T. Akamizu, M. Saji, S. Ikuyama, S. Kosugi, K. Tahara, L. D. Kohn

Section on Cell Regulation, Laboratory of Biochemistry and Metabolism, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda/USA

Abstract

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Summary

The cloning approaches of the past two years have opened new doors to the pursuit of our understanding Basedow's disease. The cloning of the TSH receptor is the most dramatic step; nevertheless, all the proteins mentioned in the following appear to be important molecules in the bioactivity of the thyroid cell and are implicated as autoantigens.

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