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Exp Clin Endocrinol Diabetes 1997; 105: 17-19
DOI: 10.1055/s-0029-1211788
© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Erythrocyte carbonic anhydrase activity in smokers and in diabetic patients

P. Abel1 , S. Wussow1 , H. Blücher2 , G. Gros3 , R. Rettig1 , A. Honig1
  • 1Institute of Physiology, Ernst-Moritz-Arndt-University Greifswald, Rubenowstr. 3, Greifswald, Germany
  • 2Clinic Karlsburg-Greifswald, Center for Diabetes and Metabolic Diseases
  • 3School of Medicine, Center for Physiology, Division of Autonomic Physiology, P.O. Box 61080, Hannover, Germany
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Publication History

Publication Date:
14 July 2009 (online)

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Summary

Carbonic anhydrase activity was measured in lyzed erythrocytes from smoking and non-smoking young men as well as from diabetic and healthy young women. Enzyme activity was determined by a changing-pH-assay, using a stirred reaction vessel and glass pH electrode.

CAA was lower in smokers than in non-smokers. Furthermore, it was lower in diabetics than in nondiabetic controls. We conclude that cigarette smoking as well as diabetes mellitus may reduce erythrocyte carbonic anhydrase activity.

Key words

carbonic anhydrase - diabetes mellitus - smokers - nonsmokers

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