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Synthesis 2010(14): 2413-2418
DOI: 10.1055/s-0029-1218770
DOI: 10.1055/s-0029-1218770
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Microwave-Assisted Synthesis of 4-Amino-2-arylthieno[2,3-d]pyrimidines and Their Subsequent Functionalization
Further Information
Received
11 March 2010
Publication Date:
05 May 2010 (online)
Publication History
Publication Date:
05 May 2010 (online)
![](https://www.thieme-connect.de/media/synthesis/201014/lookinside/thumbnails/10.1055-s-0029-1218770-1.jpg)
Abstract
New 4-amino-2-arylthieno[2,3-d]pyrimidines were synthesized by reacting 2-amino-3-cyanothiophenes and aryl nitriles under microwave irradiation. Functionalization of 4-amino group was made by acetic anhydride and several isocyanates.
Key words
2-amino-3-cyanothiophenes - 4-amino-2-arylthieno[2,3-d]pyrimidines - microwave irradiation
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