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J Knee Surg 2013; 26(S 01): S067-S071
DOI: 10.1055/s-0032-1313739
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Bilateral Diffuse Pigmented Villonodular Synovitis of the Knee

Georg Klammer
1   Department of Orthopaedics, Uniklinik Balgrist, Zurich, Switzerland
,
Michael Betz
1   Department of Orthopaedics, Uniklinik Balgrist, Zurich, Switzerland
,
Barbara Delaloye
2   Department of Radiology, Uniklinik Balgrist, Zurich, Switzerland
,
Mazda Farshad
1   Department of Orthopaedics, Uniklinik Balgrist, Zurich, Switzerland
,
Koch P. Peter
1   Department of Orthopaedics, Uniklinik Balgrist, Zurich, Switzerland
› Author Affiliations
Further Information

Publication History

22 March 2011

28 December 2011

Publication Date:
15 May 2012 (online)

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Abstract

Pigmented villonodular synovitis (PVNS) is a proliferative disease of synovial tissue characterized by lipid-laden macrophages, multinucleated giant cells, and hemosiderin deposits. PVNS presents either in a localized form with minimal rates of recurrence after surgical resection or in a diffuse form with an expansive growth pattern showing formation of osseous erosions and extra-articular manifestation. In the diffuse form high recurrence rates occur as a result of the challenge of achievement of total synovectomy. Typically only one single joint, being the knee in 80% of cases, is involved with diffuse PVNS. Reports of bi- or multiarticular manifestation are at best rare. Here, a case of a 16-year-old girl with bilateral diffuse PVNS of the knee allows discussion of diagnostic and treatment considerations.

Keywords

pigmented villonodular synovitis - knee - bilateral
 

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