Ventrikulo-Vaskuläres Coupling – Diagnostik (patho-)physiologischer kardialer und vaskulärer Zusammenhänge

Durch moderne, nicht-invasive diagnostische Methoden ist die Erkenntnis der physiologischen Zusammenhänge der kardialen und arteriellen Funktion zur klinischen Aufmerksamkeit gekommen. Linksventrikuläre und arterielle Elastanzen liegen physiologisch in einem einfachen Verhältnis, was sich bei Hypertonie verursachter diastolischer oder/und systolischer Dysfunktion respektive vermehrter arterieller Gefäßsteifigkeit verschiebt. Zur Einführung in die klinische Routine sind prospektive, klinische Studien mit dem Endpunkt der Prognostik erforderlich.

Modern, non-invasive diagnostic modalities resulted in clinical attendance of knowledge on physiologic connections of cardiac and arterial function. Left ventricular and arterial elastances are related in simple ratio, which in hypertension caused diastolic or/and systolic dysfunction and arterial stiffening respectively are distorted. For introduction into clinical routine prospective, clinical studies with the endpoint of prognosis are mandatory.

Key words

Left ventricular function - systolic - diastolic - wave intensities - elastances - e-tracking - echocardiography - pulse wave analysis

• Literatur

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