PDF herunterladen
Nuklearmedizin 1980; 19(02): 91-92
DOI: 10.1055/s-0037-1620936
Originalarbeiten – Original Articles
Schattauer GmbH

99mTc-Unithiol Complex, a New Radiopharmaceutical for Kidney Scintigraphy

IV. Autoradiographic Localisation of its Cellular Distribution in the Kidney 99mTc-Uni thiol-Komplex, ein neues Radiopharmazeutikum für die NierenszintigraphieIV. Autoradiographische Lokalisierung seiner zellularen Verteilung in der Niere
M. Ogiński
1   From the Department of Nuclear Medicine and Radiobiology and the Department of Oncology, Medical Academy, Lodz, Poland
,
I. Giryn
1   From the Department of Nuclear Medicine and Radiobiology and the Department of Oncology, Medical Academy, Lodz, Poland
,
T. Piatek
1   From the Department of Nuclear Medicine and Radiobiology and the Department of Oncology, Medical Academy, Lodz, Poland
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received: 04. Oktober 1979

Publikationsdatum:
09. Januar 2018 (online)

    Lizenzen und Reprints

Summary

The distribution of 99mTc-Unithiol complex was studied by macro-autoradiography in rats and in rabbit kidneys, and the presence of activity in the renal cortex was easily demonstrated. Using micro-autoradiography, the accumulation of activity in various parts of the nephron was observed to concentrate in the cells of the proximal and distal tubuli to a larger extent than in the glomeruli.

Zusammenfassung

Die Verteilung des 99mTc-Unithiol-Komplexes wurde makro-autoradiographisch in Ratten und in der Kaninchenniere untersucht, wobei das Vorhandensein von Radioaktivität in der Nierenrinde leicht nachgewiesen werden konnte. Mittels Mikro-Autoradiographie konnte gezeigt werden, daß die Aktivität in den Zellen der proximalen und distalen Tubuli stärker konzentriert wird als in den Glomeruli.

 

  • References

  • (1) Darte L, Oginski M, Persson R. B. R. 99mTc-Unithiol complex, a new radiopharmaceutical for kidney scintigraphy. III. Studies of labelling Unithiol with 99mTc. Nucl. Med XVIII: 26-35 1979;
    Google Scholar
  • (2) Liniecki J, Surma M, Mtodkowska E, Oginski M. 99Technetium-Unithiol complex, a new pharmaceutical for kidney scintigraphy. II. Comparison of renal scintigrams in man obtained by means of l97Hg-Chlormerodrin or99Tc-Unithiol complex. Nucl. Med XVI: 179-182 1977;
    Google Scholar
  • (3) Oginski M, Rembelska M. 99Technetium-Unithiol complex, a new pharmaceutical for kidney scintigraphy. Nucl. Med XV: 282-286 1976;
    Google Scholar
  • (4) Rohlin M. 99Tc-labelled pyrophosphate,99Tc-labelled ethylene-diphosphate and related compounds in young rats. Dep. of Oral Radiology and Oral Pathology, University of Lund, Malmö, Sweden 1977
    PubMedGoogle Scholar
  • (5) Treves S, Martinez D. A, Davis M. A, Hedley-Whyte E. T. Cellular localization of99Tc radiopharmaceuticals by radioautography. J. nucl. Med 17: 536 1976;
    Google Scholar
  • (6) Woźniak L, Oginski M, Karasek M, Piatek T. Histologische und histochemische Untersuchungen an Rattennieren nach Verabreichung von Chlormerodrin-203Hg und Unithiol. Fortschr. Röntgenstr 119: 603-609 1973;
    Artikel in Thieme ConnectGoogle Scholar