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Methods Inf Med 1985; 24(04): 197-199
DOI: 10.1055/s-0038-1635379
Original Article
Schattauer GmbH

The Use of a Personal Computer in the Pulmonary Function Tests of Laboratory Rats[*]

Anwendung eines Personal-Computers bei Lungenfunktionstests an Laboratoriumsratten
E. Massad
1   (From the Laboratory of Experimental Air Pollution of the Department of Pathology, Faculty of Medicine, University of São Paulo, and the Department of Informatics of the “Instituto do Coração HC-FMUSP”, São Paulo, Brazil)
,
S. Sh. Furuie
1   (From the Laboratory of Experimental Air Pollution of the Department of Pathology, Faculty of Medicine, University of São Paulo, and the Department of Informatics of the “Instituto do Coração HC-FMUSP”, São Paulo, Brazil)
,
L. de Assis Moura Jr.
1   (From the Laboratory of Experimental Air Pollution of the Department of Pathology, Faculty of Medicine, University of São Paulo, and the Department of Informatics of the “Instituto do Coração HC-FMUSP”, São Paulo, Brazil)
,
P. H. Nascimento Saldiva
1   (From the Laboratory of Experimental Air Pollution of the Department of Pathology, Faculty of Medicine, University of São Paulo, and the Department of Informatics of the “Instituto do Coração HC-FMUSP”, São Paulo, Brazil)
,
M. A. Nicolelis
1   (From the Laboratory of Experimental Air Pollution of the Department of Pathology, Faculty of Medicine, University of São Paulo, and the Department of Informatics of the “Instituto do Coração HC-FMUSP”, São Paulo, Brazil)
,
G. M. Böhm
1   (From the Laboratory of Experimental Air Pollution of the Department of Pathology, Faculty of Medicine, University of São Paulo, and the Department of Informatics of the “Instituto do Coração HC-FMUSP”, São Paulo, Brazil)
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Publikationsdatum:
17. Februar 2018 (online)

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Summary

A system consisting of an 8-bit word microcomputer of the APPLE line equipped with an analog-to-digital converter, connected to a physiograph measuring pressures from a whole-body Plethysmograph, was used to perform pulmonary tests in rats. The system proved to be time-saving without loss in accuracy when compared to manual calculation methods. It allows measurement repetition during the same experiment, which is impossible by manual techniques, and permits to obtain flow/volume relationships without pneumotachographs or integrator and/or differentiator modules. This approach may be applied to humans and used by any physician.

Ein aus einem 8-Bit-Mikrocomputer der APPLE-Familie bestehendes System, ausgestattet mit einem A/D-Konverter und verbunden mit einem Physiographen, der den Druck eines Ganzkörperplethysmographen mißt, wurde benutzt, um Lungenfunktionstests bei Ratten vorzunehmen.

Verglichen mit manuellen Berechnungsmethoden erwies sich das System als zeitsparend ohne Genauigkeitsverlust. Es gestattet eine Wiederholung der Messungen während desselben Versuchs, was bei manuellen Techniken unmöglich ist, und ermöglicht es, die Beziehung zwischen Atemfluß und Atemvolumen ohne Pneumotachographen oder Integratoren und/ oder Differentiatormoduls zu ermitteln. Die Methode kann auch auf Menschen angewandt und von jedem Arzt benutzt werden.

Key-Words:

Pulmonary Function - Personal Computer - Physiology - Digital-to-Analog Converter - Biological Signal Processing

Schlüssel-Wörter:

Lungenfunktion - Personal-Computer - Physiologie - A/D-Konverter - Verarbeitung biologischer Signale

* Correspondence to Prof. György M. Böhm, Av. Dr. Arnaldo, 455, Dept. Pathologia, CEP 01246, Sāo Paulo, S.P., Brazil


 

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