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Thromb Haemost 1973; 29(02): 300-312
DOI: 10.1055/s-0038-1647773
Original Article
Schattauer GmbH

Release of Fibrinopep tides from Fibrinolytic Fibrinogen Fragment E

A Peyer
1   Department of Medicine, Kantonsspital, University of Zurich Zurich, Switzerland
,
P. W Straub
1   Department of Medicine, Kantonsspital, University of Zurich Zurich, Switzerland
› Author Affiliations
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Publication History

Received: 21 September 1972

Publication Date:
30 June 2018 (online)

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Purified “terminal” proteolytic E fragments of fibrinogen and fibrin as produced by plasmin digestion were treated with thrombin. Thrombin treatment of fragment E obtained from fibrinogen, liberated both fibrinopeptides A and B and sometimes AP. Thrombin treatment of fragment E obtained from Reptilase-clotted fibrin liberated only fibrinopeptide B. From fragments E derived from thrombin-clotted fibrin as well as from fragments D obtained from either fibrinogen, thrombin-fibrin or Reptilase - fibrin no fibrinopeptides could be recovered.

 

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