Thromb Haemost 1967; 18(03/04): 612-616
DOI: 10.1055/s-0038-1655070
Originalarbeiten — Original Articles — Travaux Originaux
Schattauer GmbH

Elinin and Blood Coagulation

Nicoletta Vulpis
1   From the Institute of Internal Medicine, University of Bari, Italy (Director: Prof. Virgilio Chini)
,
G Vulpis
1   From the Institute of Internal Medicine, University of Bari, Italy (Director: Prof. Virgilio Chini)
,
C Santoro
1   From the Institute of Internal Medicine, University of Bari, Italy (Director: Prof. Virgilio Chini)
› Author Affiliations
Further Information

Publication History

Publication Date:
24 July 2018 (online)

Summary

Investigations were performed on the effects of elinin on blood coagulation. It was found that elinin exerts significant anticoagulant activity. This was demonstrated by an one-stage re calcification test, prothrombin consumption, thromboplastin and thrombin generation. The conclusion was that the anticoagulant activity of EL is probably due to the high molecular weight of its molecule.

 
  • References

  • 1 Biggs R, Macfarlane R. C. Human Blood Coagulation and its Disorders. Blackwell Scientific Publications; Oxford: 1957
  • 2 Eichelberger jr. J. W. Laboratory Methods in Blood Coagulation. Harper & Row, Publishers; New York: 1965
  • 3 Gaston L. W, Evanger A. E. The Requirement for Calcium in the Thromboplastin Generation Test. J. Lab. clin. Med. 64: 501-511 1964;
  • 4 Jacobaeus U. Studies on the Effect of Dextran on the Coagulation of Blood. Acta med. scand. 332: 1-103 1957;
  • 5 Langdell R. D, Adelson E. A, Furth F. W, Crosby W. D. Dextran and Prolonged Bleeding Time. J. Amer. med. Ass. 166: 346-351 1958;
  • 6 Moskowitz M, Dandliker W. B, Calvin M, Evans R. S. Studies on the Antigens of Human Red Cells. I. The Separation from Human Erythrocytes of a water soluble fraction. J. Immunol. 65: 383-392 1950;
  • 7 Pitney W. R, Dacie J. V. A Simple Method of Studying the Generation of Thrombin in Recalcified Plasma. J. clin. Path. 06: 9-14 1953;
  • 8 Vulpis N, Vulpis G, Giorgino R. Stroma S Protein related to the Blood Clotting Mechanism. Blut. 10: 319-328 1964;
  • 9 Vulpis G, Vulpis N, Santoro C. Characterization of a Stroma Protein. Elinin. Ital. J. Biochem. 15: 189-199 1966;