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Thromb Haemost 1985; 54(02): 438-441
DOI: 10.1055/s-0038-1657867
Original Article
Schattauer GmbH Stuttgart

Mouse Trophoblast Cells Are Constitutive Producers of Thromboplastin (Factor III) In Vitro

K Dalaker
1   The Research Institute for Internal Medicine, University of Oslo, Rikshospitalet, Oslo, Norway
3   The Department of Obstetrics and Gynecology, Rikshospitalet, Oslo, Norway
4   The Animal Department, Rikshospitalet, Oslo, Norway
,
E Haug
2   The Hormone Laboratory, Aker Hospital, Oslo, Norway
,
H Prydz
1   The Research Institute for Internal Medicine, University of Oslo, Rikshospitalet, Oslo, Norway
› Author Affiliations
Further Information

Publication History

Received 13 September 1984

Accepted 08 May 1985

Publication Date:
18 July 2018 (online)

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Summary

Trophoblasts from murine placenta synthesize thromboplastin in the absence of inducing agents and a functional complement system, nor is the rate or level of synthesis enhanced by inducers. A serum factor which is destroyed/removed by addition of oxalate and subsequent dialysis appears to enhance the ability of trophoblasts to synthesize thromboplastin.

Keywords

Thromboplastin - Tissue factor - Trophoblasts - Placenta - Synthesis - Cell culture
 

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