Download PDF
Thromb Haemost 1985; 54(04): 871-872
DOI: 10.1055/s-0038-1660151
International Committee Communications
Schattauer GmbH Stuttgart

Standard Nomenclature for Factor VIII and von Willebrand Factor: A Recommendation by the International Committee on Thrombosis and Haemostasis

V J Marder
1   The University of Rochester School of Medicine & Dentistry, Rochester, NY, USA
,
P M Mannucci
2   The A. Bianchi Bonomi Hemophilia and Thrombosis Centre, Milano, Italy
,
B G Firkin
3   The Alfred Hospital, Victoria, Australia
,
L W Hoyer
4   The American Red Cross, Bethesda, Maryland, USA
,
D Meyer
5   The Institut de Pathologie Cellulaire, Hopital Bicetre, Paris, France
› Author Affiliations
Further Information

Publication History

Received 21 August 1985

Accepted 21 August 1985

Publication Date:
19 July 2018 (online)

Also available at
  PDF Download  Permissions and Reprints
 

  • References

  • 1 Vehar GA, Davie EW. Preparation and properties of bovine factor VIII (antihemophilic factor). Biochemistry 1980; 19: 401-410
    CrossrefPubMedGoogle Scholar
  • 2 Fass DN, Knutson GJ, Katzmann JA. Monoclonal antibodies to porcine factor VIII coagulant and their use in the isolation of active coagulant protein. Blood 1982; 59: 594-600
    PubMedGoogle Scholar
  • 3 Fulcher CA, Zimmerman T S. Characterization of the human factor VIII procoagulant protein with a heterologous precipitating antibody. Proc Natl Acad Sci USA 1982; 79: 1648-1652
    CrossrefPubMedGoogle Scholar
  • 4 Rotblat F, O,Brien DP, Middleton SM, Tuddenham EG D. Purification and characterization of human factor VIII: C. Thromb Haemostas 1983; 50: 108 (Abstr)
    PubMedGoogle Scholar
  • 5 Owen WG, Wagner RH. Antihemophilic factor: Separation of an active fragment following dissociation by salts or detergents. Thrombos Diathes Haemorrh 1972; 27: 502-515
    PubMedGoogle Scholar
  • 6 Hoyer LW. Biochemistry of factor VIII. In Hemostasis and Thrombosis: Basic Principles and Clinical Practice Colman RW, Hirsh J, Marder VJ, Salzman ES. (Eds) J B Lippincott Co; Philadelphia: 1982. pp 39-53
  • 7 Zimmerman TS, Meyer D. Factor VUI-von Willebrand factor and the molecular basis of von Willebrand,s disease. In Hemostasis and Thrombosis: Basic Principles and Clinical Practice Colman RW, Hirsh J, Marder VJ, Salzman ES. (Eds) J B Lippincott Co; Philadelphia: 1982. pp 54-63
  • 8 Zimmerman TS, Ratnoff OD, Powell AE. Immunologic differentiation of classic Hemophilia (Factor VIII deficiency) and von Willebrand,s disease. J Clin Invest 1971; 50: 244-254
    CrossrefPubMedGoogle Scholar
  • 9 Howard MA, Firkin BG. Ristocetin - A new tool in the investigation of platelet aggregation. Thrombos Diathes Haemorrh 1971; 26: 362-369
    PubMedGoogle Scholar
  • 10 Shoai I, Lavergne JM, Ardaillou N, Obert B, Ala F, Meyer D. Heterogeneity of von Willebrand,s disease: Study of 40 Iranian cases. Br J Haematol 1977; 37: 67-83
    CrossrefPubMedGoogle Scholar
  • 11 Italian Working Group. Spectrum of von Willebrand,s disease: A study of 100 cases. Br J Haematol 1977; 35: 101-112
    CrossrefPubMedGoogle Scholar
  • 12 Rick ME, Hoyer LW. Immunologic studies of antihemophilic factor (AHF, factor VIII). V. Immunologic properties of AHF subunits produced by salt dissociation. Blood 1973; 42: 737-747
    PubMedGoogle Scholar
  • 13 Weiss HJ, Phillips LL, Rosner W. Separation of subunits of antihemophilic factor (AHF) by agarose gel chromatography. Thrombos Diathes Haemorrh 1972; 27: 212-219
    PubMedGoogle Scholar
  • 14 Baugh R, Brown J, Sargeant Ret al. Separation of human factor VIII activity from the von Willebrand,s antigen and ristocetin platelet aggregating activity. Biochim Biophys Acta 1974; 371: 360-367
    CrossrefPubMedGoogle Scholar
  • 15 Zimmerman TS, Edgington TS. Factor VIII coagulant activity and factor VIII-like antigen: Independent molecular entities. J Exp Med 1973; 138: 1015-1020
    CrossrefPubMedGoogle Scholar
  • 16 Graham JB. Genetics of haemostasis. In Haemostasis and Thrombosis Bloom AL, Thomas D P. (Eds) Churchill Livingstone; Edinburgh: 1981. pp 395-410
  • 17 Jaffe EA, Hoyer LW, Nachman RL. Synthesis of antihemophilic factor antigen by cultured human endothelial cells. J Clin Invest 1973; 52: 2757-2764
    CrossrefPubMedGoogle Scholar
  • 18 Nachman RL, Levine R, Jaffe EA. Synthesis of Factor VIII antigen by cultured guinea pig megakaryocytes. J Clin Invest 1977; 60: 914-921
    CrossrefPubMedGoogle Scholar
  • 19 Wagner DD, Marder VJ. Biosynthesis of von Willebrand protein by human endothelial cells. Processing steps and their intracellular localization. J Cell Biol 1984; 99: 2123-2130
    CrossrefPubMedGoogle Scholar
  • 20 Lavergne JM, Meyer D, Reisner H. Characterization of human anti-factor VIII antibodies purified by immune complex formation. Blood 1976; 48: 931-939
    PubMedGoogle Scholar
  • 21 Meyer D. Specificity and structure of factor VIII and IX antibodies in haemophiliacs. In: Haemophilia Seligsohn U, Hozoszowski H. (Eds) Castle House Pub Ltd; London: 1981. pp 69-77
  • 22 Fulcher CA, Roberts JR, Zimmerman TS. Thrombin proteolysis of purified factor VIII procoagulant protein: Correlation of activation with generation of a specific polypeptide. Blood 1983; 61: 807-811
    PubMedGoogle Scholar
  • 23 Brown JE, Thuy LP, Carton CL, Hougie C. Studies on a monoclonal antibody to human factor VIII coagulant activity, with a description of a facile two-site factor VIII coagulant antigen assay. J Lab Clin Med 1983; 101: 793-805
    PubMedGoogle Scholar
  • 24 Rotblat F, Goodall AH, O,Brien DP, Rawlings E, Middleton S, Tuddenham EG D. Monoclonal antibodies to human procoagulant factor VIII. J Lab Clin Med 1983; 101: 736-746
    PubMedGoogle Scholar
  • 25 Lazarchick J, Hoyer LW. Immunoradiometric measurement of the factor VIII procoagulant antigen. J Clin Invest 1978; 62: 1048-1052
    CrossrefPubMedGoogle Scholar
  • 26 Peake IR, Bloom AL, Giddings JC et al. An immunoradiometric assay for procoagulant factor VIII antigen: Results in haemophilia, von Willebrand,s disease and fetal plasma and serum. Br J Haematol 1979; 42: 269-281
    CrossrefPubMedGoogle Scholar
  • 27 Reisner HM, Barrow ES, Graham JB. Radioimmunoassay for coagulant factor VUI-related antigen (VIII :CAg). Throm Res 1979; 14: 235-239
    CrossrefPubMedGoogle Scholar
  • 28 Holmberg L, Borge L, Ljung Ret al. Measurement of antihaemophilic factor A antigen (VIII :CAg) with a solid phase immunoradiometric method based on homologous non-haemophilic antibodies. Scand J Haematol 1979; 23: 17-24
    PubMedGoogle Scholar
  • 29 Wood WI, Capon DJ, Simonsen CC et al. Expression of active human factor VIII from recombinant DNA clones. Nature 1984; 312: 330-337
    CrossrefPubMedGoogle Scholar
  • 30 Gitschier J, Wood WI, Goralka TM et al. Characterization of the human factor VIII gene. Nature 1984; 312: 326-330
    CrossrefPubMedGoogle Scholar
  • 31 Toole JJ, Knopf JL, Wozney JM et al. Molecular cloning of a cDNA encoding human antihaemophilic factor. Nature 1984; 312: 342-347
    CrossrefPubMedGoogle Scholar
  • 32 Lynch DC, Zimmerman TS, Collins CJ et al. Molecular cloning of cDNA for human von Willebrand factor: Authentication by a new method. Cell 1985; 41: 49-56
    CrossrefPubMedGoogle Scholar
  • 33 Ginsburg D, Handin RI, Bonthron DT et al. Human von Willebrand Factor (vWF): Isolation and complementary DNA (cDNA) clones and chromosomal localization. Science 1985; 228: 1401-1406
    CrossrefPubMedGoogle Scholar