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Semin Musculoskelet Radiol 2024; 28(05): 515-527
DOI: 10.1055/s-0044-1788692
Review Article

Bone Marrow and Metabolic Bone Disease

Maria Pilar Aparisi Gómez 
1   Department of Radiology, Te Toka Tumai Auckland (Auckland District Health Board), Grafton, Auckland, New Zealand
2   Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
3   Department of Radiology, IMSKE, València, Spain
,
Alberto Bazzocchi 
4   Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
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Abstract

The bone marrow represents one of the largest organs in the body, with a relevant metabolic role that continues to be investigated. Numerous studies have focused on marrow adipose tissue (MAT). Evidence indicates that the bone marrow adipocytes do not only work as storage tissue but also consist of endocrine and paracrine cells, with the potential to contribute to local and systemic metabolism. MAT plays a role in bone health through its interaction with the other components of bone. Many metabolic disorders (osteoporosis, obesity, diabetes) have a complex and still not well-established or understood relationship with bone health. This article surveys the literature on the relationship of bone marrow and metabolic disorders, and how it is being studied using imaging techniques, with a special focus on bone health.

Keywords

bone marrow imaging - osteoporosis - vertebral fracture - oncologic imaging - marrow adipose tissue


Publication History

Article published online:
15 October 2024

© 2024. Thieme. All rights reserved.

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