Subscribe to RSS
DOI: 10.1055/s-0044-1795074
Alignment Strategies in Total Knee Arthroplasty: The Rise and Role of Enabling Technology
Abstract
Total knee arthroplasty (TKA) remains the gold standard surgical care for end-stage knee arthritis. Since its inception, TKA has seen many transformative factors with advances in material properties, implant design, and fixation. Improvements in implant longevity has culminated in TKA being recognized as one of modern medicine's most successful surgical procedures. Patient satisfaction, however, remains a significant challenge. Recent studies report that patient satisfaction with current implants and techniques remains at 80 to 90%, suggesting that up to one in five patients remain dissatisfied with their procedure. A balanced knee, defined as equal medial and lateral gaps in knee extension and flexion, is a desired outcome in TKA. This has been shown to be associated with improved clinical outcomes. Given the poor rate of surgeon-defined balance, intraoperative knee balance can be confirmed with objective load data using sensor-embedded smart inserts or by measuring gaps using computer-assisted or robotic platforms. Currently, there is no consensus on the correct alignment or laxity targets for individualized alignment strategies in TKA, and further research in this area is required to answer this. Tremendous advances in our understanding of knee anatomy and kinematics have come to light in the recent past, and these insights have spawned interest in alternative alignment techniques in TKA. More recently, an appreciation of individual knee phenotypes and associated classification systems have provided a platform and the scientific justification behind these contemporary alignment strategies. Paired with enabling technologies, it is becoming an accepted paradigm that surgeons have the ability to select a desired alignment target when undertaking an individualized alignment strategy in TKA and execute the surgery with a high degree of precision. It is hoped that this may reduce the rate of dissatisfaction following TKA and improve clinical outcomes. This review article provides an overview of the concepts of knee phenotypes, current alignment strategies in TKA, and the emerging benefits of enabling technologies.
Publication History
Received: 07 August 2024
Accepted: 15 October 2024
Article published online:
06 December 2024
© 2024. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
-
References
- 1 Hirschmann MT, Moser LB, Amsler F, Behrend H, Leclerq V, Hess S. Functional knee phenotypes: a novel classification for phenotyping the coronal lower limb alignment based on the native alignment in young non-osteoarthritic patients. Knee Surg Sports Traumatol Arthrosc 2019; 27 (05) 1394-1402
- 2 Oussedik S, Haddad FS. The target may be the key to the outcome of knee arthroplasty. Bone Joint J 2024; 106-B (05) 420-421
- 3 MacDessi SJ, Griffiths-Jones W, Harris IA, Bellemans J, Chen DB. Coronal plane alignment of the knee (CPAK) classification. Bone Joint J 2021; 103-B (02) 329-337
- 4 MacDessi SJ, Griffiths-Jones W, Harris IA, Bellemans J, Chen DB. The arithmetic HKA (aHKA) predicts the constitutional alignment of the arthritic knee compared to the normal contralateral knee: a matched-pairs radiographic study. Bone Jt Open 2020; 1 (07) 339-345
- 5 Pagan CA, Karasavvidis T, Lebrun DG, Jang SJ, MacDessi SJ, Vigdorchik JM. Geographic variation in knee phenotypes based on the coronal plane alignment of the knee classification: a systematic review. J Arthroplasty 2023; 38 (09) 1892-1899.e1
- 6 Toyooka S. et al. Distribution of coronal plane alignment of the knee classification in patients with knee osteoarthritis in Japan. J Knee Surg 2022
- 7 Sappey-Marinier E, Batailler C, Swan J. et al. Mechanical alignment for primary TKA may change both knee phenotype and joint line obliquity without influencing clinical outcomes: a study comparing restored and unrestored joint line obliquity. Knee Surg Sports Traumatol Arthrosc 2022; 30 (08) 2806-2814
- 8 MacDessi SJ, van de Graaf VA, Wood JA, Griffiths-Jones W, Bellemans J, Chen DB. Not all knees are the same. Bone Joint J 2024; 106-B (06) 525-531
- 9 Insall J, Ranawat CS, Scott WN, Walker P. Total condylar knee replacement: preliminary report. 1976. Clin Orthop Relat Res 2001; (388) 3-6
- 10 Australian Orthopaedic Association National Joint Replacement Registry. Annual Rep 2024; 371-384
- 11 Antonios JK, Korber S, Sivasundaram L. et al. Trends in computer navigation and robotic assistance for total knee arthroplasty in the United States: an analysis of patient and hospital factors. Arthroplast Today 2019; 5 (01) 88-95
- 12 Bathis H, Perlick L, Tingart M, Luring C, Zurakowski D, Grifka J. Alignment in total knee arthroplasty. A comparison of comuter-assisted surgery with the conventional technique. J Bone Joint Surg Br 2004; 86 (05) 682-687
- 13 Sikorski JM. Alignment in total knee replacement. J Bone Joint Surg Br 2008; 90 (09) 1121-1127
- 14 Haaker RG, Stockheim M, Kamp M, Proff G, Breitenfelder J, Ottersbach A. Computer-assisted navigation increases precision of component placement in total knee arthroplasty. Clin Orthop Relat Res 2005; 433 (433) 152-159
- 15 McEwen P. et al. Computer assisted kinematic and mechanical axis total knee arthroplasty: a prospective randomized controlled trial of bilateral simultaneous surgery. J Arthroplasty 2019
- 16 Viskontas DG, Skrinskas TV, Johnson JA, King GJ, Winemaker MJ, Chess DG. Computer-assisted gap equalization in total knee arthroplasty. J Arthroplasty 2007; 22 (03) 334-342
- 17 Nam D, Nunley RM, Barrack RL. Patient dissatisfaction following total knee replacement: a growing concern?. Bone Joint J 2014; 96-B (11) )(Suppl A) 96-100
- 18 Panjwani TR, Mullaji A, Doshi K, Thakur H. Comparison of functional outcomes of computer-assisted vs conventional total knee arthroplasty: a systematic review and meta-analysis of high-quality, prospective studies. J Arthroplasty 2019; 34 (03) 586-593
- 19 van der List JP, Chawla H, Pearle AD. Robotic-assisted knee arthroplasty: an overview. Am J Orthop 2016; 45 (04) 202-211
- 20 Lang JE, Mannava S, Floyd AJ. et al. Robotic systems in orthopaedic surgery. J Bone Joint Surg Br 2011; 93 (10) 1296-1299
- 21 Allom RJ, Wood JA, Chen DB, MacDessi SJ. Tibiofemoral dynamic stressed gap laxities correlate with compartment load measurements in robotic arm-assisted total knee arthroplasty. Bone Jt Open 2021; 2 (11) 974-980
- 22 Clark GW, Esposito CI, Wood D. Individualized functional knee alignment in total knee arthroplasty: a robotic-assisted technique. Tech Orthopaed 2022; 37 (3) 185-191
- 23 Kayani B, Konan S, Pietrzak JRT, Haddad FS. Iatrogenic bone and soft tissue trauma in robotic-arm assisted total knee arthroplasty compared with conventional jig-based total knee arthroplasty: a prospective cohort study and validation of a new classification system. J Arthroplasty 2018; 33 (08) 2496-2501
- 24 Jacofsky DJ, Allen M. Robotics in arthroplasty: a comprehensive review. J Arthroplasty 2016; 31 (10) 2353-2363
- 25 Joo PY, Chen AF, Richards J. et al. Clinical results and patient-reported outcomes following robotic-assisted primary total knee arthroplasty: a multicentre study. Bone Jt Open 2022; 3 (08) 589-595
- 26 Keeney JA. Innovations in total knee arthroplasty: improved technical precision, but unclear clinical benefits. Orthopedics 2016; 39 (04) 217-220
- 27 Parratte S, Pagnano MW, Trousdale RT, Berry DJ. Effect of postoperative mechanical axis alignment on the fifteen-year survival of modern, cemented total knee replacements. J Bone Joint Surg Am 2010; 92 (12) 2143-2149
- 28 Abdel MP, Ollivier M, Parratte S, Trousdale RT, Berry DJ, Pagnano MW. Effect of postoperative mechanical axis alignment on survival and functional outcomes of modern total knee arthroplasties with cement: a concise follow-up at 20 years. J Bone Joint Surg Am 2018; 100 (06) 472-478
- 29 MacDessi SJ, Oussedik S, Abdel MP, Victor J, Pagnano MW, Haddad FS. The language of knee alignment: updated definitions and considerations for reporting outcomes in total knee arthroplasty. Bone Joint J 2023; 105-B (02) 101-101
- 30 Abdel MP, Oussedik S, Parratte S, Lustig S, Haddad FS. Coronal alignment in total knee replacement: historical review, contemporary analysis, and future direction. Bone Joint J 2014; 96-B (07) 857-862
- 31 Golladay GJ, Bradbury TL, Gordon AC. et al. Are patients more satisfied with a balanced total knee arthroplasty?. J Arthroplasty 2019; 34 (7S): S195-S200
- 32 MacDessi SJ, Gharaibeh MA, Harris IA. How accurately can soft tissue balance be determined in total knee arthroplasty?. J Arthroplasty 2019; 34 (02) 290-294.e1
- 33 Gharaibeh MA, Chen DB, MacDessi SJ. Soft tissue balancing in total knee arthroplasty using sensor-guided assessment: is there a learning curve?. ANZ J Surg 2018; 88 (05) 497-501
- 34 Bensa A, Sangiorgio A, Deabate L, Illuminati A, Pompa B, Filardo G. Robotic-assisted mechanically aligned total knee arthroplasty does not lead to better clinical and radiological outcomes when compared to conventional TKA: a systematic review and meta-analysis of randomized controlled trials. Knee Surg Sports Traumatol Arthrosc 2023; 31 (11) 4680-4691
- 35 Corban LE, van de Graaf VA, Chen DB, Wood JA, Diwan AD, MacDessi SJ. How often do we alter constitutional limb alignment, joint line obliquity, and coronal plane alignment of the knee (CPAK) phenotype when performing mechanically aligned TKA?. Bone Jt Open 2024; 5 (02) 109-116
- 36 Waterson H, Walker R, Koopmans P. et al. Gap balanced adjusted mechanical alignment versus measured resection mechanical alignment: a randomised controlled trial. Arch Orthop Trauma Surg 2023; 143 (04) 2141-2151
- 37 Howell SM, Kuznik K, Hull ML, Siston RA. Results of an initial experience with custom-fit positioning total knee arthroplasty in a series of 48 patients. Orthopedics 2008; 31 (09) 857-863
- 38 Howell SM, Papadopoulos S, Kuznik KT, Hull ML. Accurate alignment and high function after kinematically aligned TKA performed with generic instruments. Knee Surg Sports Traumatol Arthrosc 2013; 21 (10) 2271-2280
- 39 Howell SM, Papadopoulos S, Kuznik K, Ghaly LR, Hull ML. Does varus alignment adversely affect implant survival and function six years after kinematically aligned total knee arthroplasty?. Int Orthop 2015; 39 (11) 2117-2124
- 40 MacDessi SJ. Restricted kinematic alignment in total knee arthroplasty: scientific exploration involving detailed planning, precise execution, and knowledge of when to abort. Arthroplast Today 2021; 10: 24-26
- 41 Winnock de Grave P, Luyckx T, Claeys K. et al. Higher satisfaction after total knee arthroplasty using restricted inverse kinematic alignment compared to adjusted mechanical alignment. Knee Surg Sports Traumatol Arthrosc 2022; 30 (02) 488-499
- 42 Oussedik S, Abdel MP, Victor J, Pagnano MW, Haddad FS. Alignment in total knee arthroplasty. Bone Joint J 2020; 102-B (03) 276-279
- 43 Clark G, Steer R, Wood D. Functional alignment achieves a more balanced total knee arthroplasty than either mechanical alignment or kinematic alignment prior to soft tissue releases. Knee Surg Sports Traumatol Arthrosc 2023
- 44 MacDessi SJ, Allom RJ, Griffiths-Jones W, Chen DB, Wood JA, Bellemans J. The importance of joint line obliquity: a radiological analysis of restricted boundaries in normal knee phenotypes to inform surgical decision making in kinematically aligned total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 2022; 30 (09) 2931-2940
- 45 Van de Graaf VA, Chen DB, Allom RJ, Wood JA, MacDessi SJ. Functional alignment in total knee arthroplasty best achieves balanced gaps and minimal bone resections: an analysis comparing mechanical, kinematic and functional alignment strategies. Knee Surg Sports Traumatol Arthrosc 2023; 31 (11) 5118-5127
- 46 Shatrov J, Benoit C, Batailler C, Servien E, Walter B, Lustig S. Alignment philosophy influences trochlea recreation in total knee arthroplasty: a comparative study using image-based robotic technology. Int Orthop 2023; 47 (02) 329-341
- 47 Clark GW, Steer RA, Khan RN, Collopy DM, Wood D. Maintaining joint line obliquity optimizes outcomes of functional alignment in total knee arthroplasty in patients with constitutionally varus knees. J Arthroplasty 2023; 38 (07, Suppl 2): S239-S244
- 48 Ettinger M, Tuecking LR, Savov P, Windhagen H. Higher satisfaction and function scores in restricted kinematic alignment versus mechanical alignment with medial pivot design total knee arthroplasty: a prospective randomised controlled trial. Knee Surg Sports Traumatol Arthrosc 2024; 32 (05) 1275-1286
- 49 Pangaud C, Siboni R, Gonzalez JF. et al; Writing Committee. Restoring the preoperative phenotype according to the coronal plane alignment of the knee classification after total knee arthroplasty leads to better functional results. J Arthroplasty 2024; S0883-5403 (24)00611-9